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Cat. No.: HY-N3924

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Ganoderiol F

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Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines.

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Pureté: 99.85%
CAS No.: 114567-47-4
Formule: C₃₀H₄₆O₃
Masse moléculaire:454.68

Stockage:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Ganoderiol F Chemical Structure

CAS No.: 114567-47-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF S-180	IC₅₀	7.1 μg/mL Compound: 15	Cytotoxicity against mouse S180 cells Cytotoxicity against mouse S180 cells	[PMID: 23092389]
HEK293	EC₅₀	5 μM Compound: 14	Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay	[PMID: 22014750]
HeLa	IC₅₀	5 μM Compound: 15	Cytotoxicity against human HeLa cells Cytotoxicity against human HeLa cells	[PMID: 23092389]
Hep 3B2	IC₅₀	25.3 μM Compound: 15	Cytotoxicity against human Hep3B cells Cytotoxicity against human Hep3B cells	[PMID: 23092389]
HepG2	IC₅₀	17 μM Compound: 15	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 23092389]
HepG2	IC₅₀	20.7 μM Compound: 2	Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 24974349]
Huh-7	IC₅₀	8.5 μM Compound: 15	Cytotoxicity against human HuH7 cells Cytotoxicity against human HuH7 cells	[PMID: 23092389]
K562	IC₅₀	4 μM Compound: 15	Cytotoxicity against human K562 cells Cytotoxicity against human K562 cells	[PMID: 23092389]
K562	IC₅₀	54.9 μM Compound: 22	Cytotoxicity against human K562 cells by MTT method Cytotoxicity against human K562 cells by MTT method	[PMID: 26287401]
Lewis lung carcinoma cell line	IC₅₀	2 μg/mL Compound: 15	Cytotoxicity against mouse LLC cells Cytotoxicity against mouse LLC cells	[PMID: 23092389]
PC-3	IC₅₀	79.5 μM Compound: 22	Cytotoxicity against human PC3 cells by MTT method Cytotoxicity against human PC3 cells by MTT method	[PMID: 26287401]
RAW264.7	IC₅₀	36 μM Compound: 7	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method	[PMID: 23357630]
T47D	IC₅₀	3 μg/mL Compound: 15	Cytotoxicity against human T47D cells Cytotoxicity against human T47D cells	[PMID: 23092389]

Chemical Information

CAS No. 114567-47-4
Appearance Solid
Masse moléculaire 454.68
Formule C₃₀H₄₆O₃
Color White to off-white
SMILES

C[C@]1(CC[C@]2([H])[C@H](C)CC/C=C(CO)/CO)C(C3=CC[C@@]12C)=CC[C@](C(C)4C)([H])[C@@]3(CCC4=O)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
- Microorganisms
Ganoderma amboinense
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chang UM, et al. Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells. Life Sci. 2006;79(12):1129-1139. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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Ganoderiol F

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Activité biologique

Chemical Information

Pureté et documentation

Références

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Ganoderiol F Related Classifications

HY-N3924 Related Classifications