GPS491
GPS491 (EC50 = 0.47 μM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.
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- CAS No.: 2655502-29-5
- Formule: C13H5F6N3OS2
- Masse moléculaire:397.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | CC50 |
2.51 μM
Compound: 29; GPS491
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Cytotoxicity against human PBMC cells assessed as cell viability measured after 11 days by Viacount assay
Cytotoxicity against human PBMC cells assessed as cell viability measured after 11 days by Viacount assay
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[PMID: 34795872] |
Chemical Information
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CAS No. 2655502-29-5
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Masse moléculaire 397.32
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Formule C13H5F6N3OS2
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SMILES
O=C(NC1=NC(C=CC(C(F)(F)F)=C2)=C2S1)C3=CN=C(C(F)(F)F)S3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GPS491 Related Classifications
HY-139850 Related Classifications
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