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Cat. No.: HY-165528

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Histamine glutarimide

(Synonyms: XC8)

Histamine glutarimide (XC8) is an orally active anti-asthma agent. Histamine glutarimide blocks the maturation of chemokines (CCL2, CCL7, CCL8, CCL13) and inhibits the migration of eosinophils and the degranulation of mast cells. In asthma models induced by carrageenan and rat ovalbumin, Histamine glutarimide can reduce airway resistance and the count of eosinophils in bronchoalveolar lavage fluid. Histamine glutarimide can be used in asthma research.

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CAS No.: 1464897-15-1
Formule: C₁₀H₁₃N₃O₂
Masse moléculaire:207.23

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Histamine glutarimide Chemical Structure

CAS No.: 1464897-15-1

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Description

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Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 1464897-15-1
Masse moléculaire 207.23
Formule C₁₀H₁₃N₃O₂
SMILES

O=C1N(CCC2=CN=CN2)C(CCC1)=O
Synonyms

XC8
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Renner A, et al. Safety, pharmacokinetics and pharmacodynamics of a novel anti-asthmatic drug, XC8, in healthy probands. Pulm Pharmacol Ther. 2019 Dec;59:101852. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Histamine glutarimide

Voir tous les produits spécifiques à Isoform CCR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Histamine glutarimide Related Classifications

HY-165528 Related Classifications