Hypocrellin A (Standard)
Hypocrellin A (Standard) is the analytical standard of Hypocrellin A. This product is intended for research and analytical applications. Hypocrellin A is a PKC inhibitor that exerts antidiabetic activity by reversing the effects of high glucose on endothelin (ET-1) expression. Hypocrellin A is also a photosensitizer for photodynamic therapy (PDT) with anticancer, antibacterial and antiviral activities, especially against human immunodeficiency virus (HIV). In addition, Hypocrellin-A also possesses anti-Leishmania activity (IC50=0.27 μg/ml)[1][2][3][4][5][6][7][8][9].
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- CAS No.: 77029-83-5
- Formule: C30H26O10
- Masse moléculaire:546.52
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-N2575
Hypocrellin APhotosensitizer -
HY-13689
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HY-10230
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HY-10343
SotrastaurinPan-PKC Inhibitor -
HY-10183
Go6976PKC Inhibitor -
HY-15141
StaurosporinePKC/PKA Inhibitor -
HY-B1743A
Puromycin dihydrochlorideProtein Synthesis Inhibitor -
HY-13866
Ro 31-8220 mesylatePCK Inhibitor -
HY-N0135
Tanshinone IIAVEGFR Inhibitor -
HY-101569
DarovasertibPKC Inhibitor -
HY-N1453
Hypocrellin BAnti-Fungal Agent -
HY-N0021
VerbascosideBacterial Inhibitor
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 77029-83-5
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Masse moléculaire 546.52
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Formule C30H26O10
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SMILES
COC(C1=O)=C2C3=C(C1=C(C=C4OC)O)C4=C(C(OC)=CC(O)=C56)C5=C3C(CC(C)(O)C2C(C)=O)=C(OC)C6=O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Dang L, et al. Effects of hypocrellin A on expression of vascular endothelial growth factor and endothelin-1 in human umbilical endothelial cells. Am J Chin Med. 2007;35(4):713-23. [Content Brief]
[2]. Ma YJ, et al. Enhanced Production of Hypocrellin A in Submerged Cultures of Shiraia bambusicola by Red Light. Photochem Photobiol. 2019 May;95(3):812-822. [Content Brief]
[3]. Fehr MJ, et al. Roles of oxygen and photoinduced acidification in the light-dependent antiviral activity of hypocrellin A. Biochemistry. 1995 Dec 5;34(48):15845-8. [Content Brief]
[4]. Ma G, et al. Antimicrobial and antileishmanial activities of hypocrellins A and B. Antimicrob Agents Chemother. 2004 Nov;48(11):4450-2. [Content Brief]
[5]. Hirayama, et al. "Photoinactivation of virus infectivity by hypocrellin A." Photochemistry and photobiology 66.5 (1997): 697-700. [Content Brief]
[6]. Deininger, et al. "Release of regulators of angiogenesis following Hypocrellin-A and-B photodynamic therapy of human brain tumor cells." Biochemical and Biophysical Research Communications 298.4 (2002): 520-530. [Content Brief]
[7]. Yujie, et al. "Photodynamic antimicrobial activity of hypocrellin A." Journal of Photochemistry and Photobiology B: Biology 103.1 (2011): 29-34. [Content Brief]
[8]. Yang, et al. "Hypocrellin A exerts antitumor effects by inhibiting the FGFR1 signaling pathway in non-small cell lung cancer." Phytomedicine 97 (2022): 153924. [Content Brief]
[9]. Guo, et al. "Evaluation of hypocrellin A-loaded lipase sensitive polymer micelles for intervening methicillin-resistant Staphylococcus Aureus antibiotic-resistant bacterial infection." Materials Science and Engineering: C 106 (2020): 110230. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hypocrellin A (Standard) Related Classifications
HY-N2575R Related Classifications
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