ITK antagonist
ITK antagonist (compound 10 n) is a potent, orally active and selective ITK (Interleukin-2 inducible T-cell kinase) antagonist (IC50=1 and 20 nM in different assays). ITK antagonist inhibits insulin receptor kinase (IRK) with an IC50 of 160 nM.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1149753-56-9
- Formule: C26H34N6O2S
- Masse moléculaire:494.65
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| T-cell | IC50 |
20 nM
Compound: 10n
|
Inhibition of anti-CD3 and anti-CD28 monoclonal antibody-stimulated IL2 secretion in human CD4+ T cells
Inhibition of anti-CD3 and anti-CD28 monoclonal antibody-stimulated IL2 secretion in human CD4+ T cells
|
[PMID: 19246196] |
Chemical Information
-
CAS No. 1149753-56-9
-
Masse moléculaire 494.65
-
Formule C26H34N6O2S
-
SMILES
CC(C)(O)CN1C2=CC=C(CN[C@@H](C)C(C)(C)C)C=C2N=C1NC(C3=CC=C(C4=CNN=C4)S3)=O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ITK antagonist Related Classifications
HY-13232 Related Classifications
Powered by Bioz