JW67 (Standard)

JW67 (Standard) is the analytical standard of JW67 (HY-108442). This product is intended for research and analytical applications. JW67 inhibits the canonical Wnt signaling with an IC50 of 1.17μM. JW67 affects the multiprotein complex consisting of β-catenin/GSK-3β/AXIN/APC/CK1 that rapidly reduces active β-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth.

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  • CAS No.: 442644-28-2
  • Formule: C21H18N2O6
  • Masse moléculaire:394.38
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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