Cat. No.: HY-N0658

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L-Threonine

3 Cited Publications

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Based on 3 publication(s) in Google Scholar

L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed.

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Pureté: 98.0%
CAS No.: 72-19-5
Formule: C₄H₉NO₃
Masse moléculaire:119.12

Stockage:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

L-Threonine Chemical Structure

CAS No.: 72-19-5

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Publications (3)
Solvant et solubilité
- In Vitro
- In Vivo
Pureté et documentation
Références
Help & FAQs
Classifications
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Activité biologique

Description

L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed^[1]^[2].

IC₅₀ & Target

Microbial Metabolite

Human Endogenous Metabolite

Voir tous les produits spécifiques à Isoform Endogenous Metabolite :

In Vitro

L-Threonine is used almost exclusively as a feed additive, primarily in feed for pigs and poultry^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 72-19-5
Appearance Solid
Masse moléculaire 119.12
Formule C₄H₉NO₃
Color White to off-white
SMILES

N[C@@H]([C@H](O)C)C(O)=O
Initial Source
- Endogenous metabolite
- Human Gut Microbiota Metabolites
- Microorganisms
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Publications (3)

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Journal Impact Factor

Nature

Lithocholic acid phenocopies anti-ageing effects of calorie restriction. [Abstract]

2025 Jul;643(8070):192-200. PMID: 39695227
Acta Pharm Sin B

Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1 α/NF- κ B feedback pathway to inhibit liver fibrosis. [Abstract]

2022 Sep;12(9):3618-3638. PMID: 36176909
Amino Acids

Identification of amino acids metabolomic profiling in human plasma distinguishes lupus nephritis from systemic lupus erythematosus. [Abstract]

2024 Sep 18;56(1):56. PMID: 39292313

Solvant et solubilité

In Vitro:

H₂O : 33.33 mg/mL (279.80 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

8.3949 mL

41.9745 mL

83.9490 mL

5 mM

1.6790 mL

8.3949 mL

16.7898 mL

10 mM

0.8395 mL

4.1974 mL

8.3949 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

In Vivo:

Working Solution

For the following dissolution methods, please prepare the working solution directly:

It is recommended to prepare fresh solutions and use them promptly within a short period of time.

The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS

Solubility: 50 mg/mL (419.74 mM); Clear solution; Need ultrasonic

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhao H, et al. Increasing L-threonine production in Escherichia coli by engineering the glyoxylate shunt and the L-threonine biosynthesis pathway. Appl Microbiol Biotechnol. 2018 Jul;102(13):5505-5518. [Content Brief]

[2]. Rie, et al. "l-Threonine." Amino Acid Biosynthesis Pathways, Regulation and Metabolic Engineering (2006): 71-92.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
H₂O	1 mM	8.3949 mL	41.9745 mL	83.9490 mL	209.8724 mL
	5 mM	1.6790 mL	8.3949 mL	16.7898 mL	41.9745 mL
	10 mM	0.8395 mL	4.1974 mL	8.3949 mL	20.9872 mL
	15 mM	0.5597 mL	2.7983 mL	5.5966 mL	13.9915 mL
	20 mM	0.4197 mL	2.0987 mL	4.1974 mL	10.4936 mL
	25 mM	0.3358 mL	1.6790 mL	3.3580 mL	8.3949 mL
	30 mM	0.2798 mL	1.3991 mL	2.7983 mL	6.9957 mL
	40 mM	0.2099 mL	1.0494 mL	2.0987 mL	5.2468 mL
	50 mM	0.1679 mL	0.8395 mL	1.6790 mL	4.1974 mL
	60 mM	0.1399 mL	0.6996 mL	1.3991 mL	3.4979 mL
	80 mM	0.1049 mL	0.5247 mL	1.0494 mL	2.6234 mL
	100 mM	0.0839 mL	0.4197 mL	0.8395 mL	2.0987 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Keywords

L-Threonine

3 Cited Publications

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L-Threonine

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Publications Citing Use of MedChemExpress (MCE) L-Threonine

Voir tous les produits spécifiques à Isoform Endogenous Metabolite

Activité biologique

Chemical Information

Publications (3)

Solvant et solubilité

Pureté et documentation

Références

Help & FAQs

Complete Stock Solution Preparation Table

L-Threonine Related Classifications

HY-N0658 Related Classifications