L-Threonine-13C4
Based on 1 publication(s) in Google Scholar
L-Threonine-13C4 is the 13C labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.93%
- CAS 番号: 55443-53-3
- 分子式: 13C4H9NO3
- 分子量:123.09
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
MedChemExpress(MCE)の使用を引用している文献 L-Threonine-13C4
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生物活性
製品説明
体外実験
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 55443-53-3
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非標識Cas 72-19-5
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性状 Solid
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分子量 123.09
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分子式 13C4H9NO3
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Color White to off-white
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SMILES
N[13C@H]([13C](O)=O)[13C@@H]([13CH3])O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Nat Commun
Pathways and selectivity of Fenton degradation of different precursor species of dissolved organic matter. [Abstract]2025 Jul 10;16(1):6361. PMID: 40640206
溶剤 & 溶解度
体外:
H2O : 100 mg/mL (812.41 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
純度とドキュメンテーション
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データシート (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Zhao H, et al. Increasing L-threonine production in Escherichia coli by engineering the glyoxylate shunt and the L-threonine biosynthesis pathway. Appl Microbiol Biotechnol. 2018 Jul;102(13):5505-5518. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 8.1241 mL | 40.6207 mL | 81.2414 mL | 203.1034 mL |
| 5 mM | 1.6248 mL | 8.1241 mL | 16.2483 mL | 40.6207 mL | |
| 10 mM | 0.8124 mL | 4.0621 mL | 8.1241 mL | 20.3103 mL | |
| 15 mM | 0.5416 mL | 2.7080 mL | 5.4161 mL | 13.5402 mL | |
| 20 mM | 0.4062 mL | 2.0310 mL | 4.0621 mL | 10.1552 mL | |
| 25 mM | 0.3250 mL | 1.6248 mL | 3.2497 mL | 8.1241 mL | |
| 30 mM | 0.2708 mL | 1.3540 mL | 2.7080 mL | 6.7701 mL | |
| 40 mM | 0.2031 mL | 1.0155 mL | 2.0310 mL | 5.0776 mL | |
| 50 mM | 0.1625 mL | 0.8124 mL | 1.6248 mL | 4.0621 mL | |
| 60 mM | 0.1354 mL | 0.6770 mL | 1.3540 mL | 3.3851 mL | |
| 80 mM | 0.1016 mL | 0.5078 mL | 1.0155 mL | 2.5388 mL | |
| 100 mM | 0.0812 mL | 0.4062 mL | 0.8124 mL | 2.0310 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.