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Cat. No.: HY-175665

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LC3 liagnd-2

LC3 liagnd-2 is an E3 ligase ligand. LC3 liagnd-2 can be used for synthesis of PROTAC PDEδ autophagic degrader 1 (HY-157458).

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CAS No.: 2839637-57-7
Formule: C₁₇H₁₀Br₂INO₄
Masse moléculaire:578.98

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

LC3 liagnd-2 Chemical Structure

CAS No.: 2839637-57-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

LC3 liagnd-2 is an E3 ligase ligand. LC3 liagnd-2 can be used for synthesis of PROTAC PDEδ autophagic degrader 1 (HY-157458)^[1].

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Chemical Information

CAS No. 2839637-57-7
Masse moléculaire 578.98
Formule C₁₇H₁₀Br₂INO₄
SMILES

O=C(O)COC1=C(Br)C=C(/C=C2C(NC3=C\2C=C(I)C=C3)=O)C=C1Br
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Bao J, et al. Discovery of Novel PDEδ Autophagic Degraders: A Case Study of Autophagy-Tethering Compound (ATTEC). ACS Med Chem Lett. 2023 Dec 29;15(1):29-35. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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LC3 liagnd-2

Voir tous les produits spécifiques à Isoform Ligands for E3 Ligase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

LC3 liagnd-2 Related Classifications

HY-175665 Related Classifications