m-PEG11-acid
Based on 1 Customer Validation
m-PEG11-acid is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG11-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Pureté: 98.0%
- CAS No.: 2280998-74-3
- Formule: C24H48O13
- Masse moléculaire:544.63
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Stockage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform ADC Linkers
MoreVoir tous les produits spécifiques à Isoform PROTAC Linkers
More
Activité biologique
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PEGs |
Non-cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2280998-74-3
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Appearance Liquid (Density: 1.113±0.06 g/cm3)
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Masse moléculaire 544.63
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Formule C24H48O13
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Color Colorless to light yellow
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SMILES
OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvant et solubilité
DMSO : 100 mg/mL (183.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8361 mL | 9.1805 mL | 18.3611 mL | 45.9027 mL |
| 5 mM | 0.3672 mL | 1.8361 mL | 3.6722 mL | 9.1805 mL | |
| 10 mM | 0.1836 mL | 0.9181 mL | 1.8361 mL | 4.5903 mL | |
| 15 mM | 0.1224 mL | 0.6120 mL | 1.2241 mL | 3.0602 mL | |
| 20 mM | 0.0918 mL | 0.4590 mL | 0.9181 mL | 2.2951 mL | |
| 25 mM | 0.0734 mL | 0.3672 mL | 0.7344 mL | 1.8361 mL | |
| 30 mM | 0.0612 mL | 0.3060 mL | 0.6120 mL | 1.5301 mL | |
| 40 mM | 0.0459 mL | 0.2295 mL | 0.4590 mL | 1.1476 mL | |
| 50 mM | 0.0367 mL | 0.1836 mL | 0.3672 mL | 0.9181 mL | |
| 60 mM | 0.0306 mL | 0.1530 mL | 0.3060 mL | 0.7650 mL | |
| 80 mM | 0.0230 mL | 0.1148 mL | 0.2295 mL | 0.5738 mL | |
| 100 mM | 0.0184 mL | 0.0918 mL | 0.1836 mL | 0.4590 mL |
m-PEG11-acid Related Classifications
HY-140501 Related Classifications
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