Mal-PEG4-VA-PBD
Based on 1 publication(s) in Google Scholar
Mal-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA.
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- Pureté : 88.94%
- CAS No.: 1342820-68-1
- Formule: C68H79N9O17
- Masse moléculaire:1294.40
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Stockage:
-80°C, stored under nitrogen
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Mal-PEG4-VA-PBD
MoreVoir tous les produits spécifiques à Isoform Antibiotic
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Activité biologique
Description
IC50 & Target
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Pyrrolobenzodiazepines |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1342820-68-1
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Appearance Solid
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Masse moléculaire 1294.40
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Formule C68H79N9O17
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Color Light yellow to yellow
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SMILES
[H][C@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@@]6([H])N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN9C(C=CC9=O)=O)=O)=O)=O)=O)C=C8)C1
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Livraison
Shipping with dry ice.
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Stockage
-80°C, stored under nitrogen
Publications (1)
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Journal Impact Factor
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Most Recent
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (77.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (245 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7726 mL | 3.8628 mL | 7.7256 mL | 19.3140 mL |
| 5 mM | 0.1545 mL | 0.7726 mL | 1.5451 mL | 3.8628 mL | |
| 10 mM | 0.0773 mL | 0.3863 mL | 0.7726 mL | 1.9314 mL | |
| 15 mM | 0.0515 mL | 0.2575 mL | 0.5150 mL | 1.2876 mL | |
| 20 mM | 0.0386 mL | 0.1931 mL | 0.3863 mL | 0.9657 mL | |
| 25 mM | 0.0309 mL | 0.1545 mL | 0.3090 mL | 0.7726 mL | |
| 30 mM | 0.0258 mL | 0.1288 mL | 0.2575 mL | 0.6438 mL | |
| 40 mM | 0.0193 mL | 0.0966 mL | 0.1931 mL | 0.4828 mL | |
| 50 mM | 0.0155 mL | 0.0773 mL | 0.1545 mL | 0.3863 mL | |
| 60 mM | 0.0129 mL | 0.0644 mL | 0.1288 mL | 0.3219 mL |
Mal-PEG4-VA-PBD Related Classifications
HY-126685 Related Classifications
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