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Cat. No.: HY-10886

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MCOPPB

Name: MCOPPB
Brand: MedChemExpress
SKU: HY-10886
Availability: PreOrder

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

MCOPPB is an orally active and selective agonist of Nociceptin/Orphanin FQ–Receptor. MCOPPB inhibits signaling through the NOP receptor in the mouse brain. MCOPPB is used in anxiety disorders research.

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CAS No.: 1028969-49-4
Formule: C₂₆H₄₀N₄
Masse moléculaire:408.62

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

MCOPPB Chemical Structure

CAS No.: 1028969-49-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-13044

ADL-5859 hydrochloride

Activité biologique
- Description
- Cellular Effect
Chemical Information
Publications (1)
Pureté et documentation
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Opioid Receptor :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO-K1	EC₅₀	34 nM Compound: 1, MCOPPB	Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding	[PMID: 19125610]
CHO-K1	EC₅₀	4696 nM Compound: 1, MCOPPB	Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding	[PMID: 19125610]
HEK293	EC₅₀	0.39 nM Compound: 1, MCOPPB	Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS binding Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS binding	[PMID: 19125610]
HEK293	EC₅₀	80 nM Compound: 1, MCOPPB	Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding	[PMID: 19125610]

Chemical Information

CAS No. 1028969-49-4
Masse moléculaire 408.62
Formule C₂₆H₄₀N₄
SMILES

CC1(N2CCC(N3C4=CC=CC=C4N=C3[C@H]5CNCCC5)CC2)CCCCCCC1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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RSC Med Chem

Probing non-peptide agonists binding at the human nociceptin/orphanin FQ receptor: a molecular modelling study. [Abstract]

2024 Dec 10. PMID: 39790123

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hirao A, et al. Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent. J Pharmacol Sci. 2008 Mar;106(3):361-8. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MCOPPB

1 Cited Publications

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Activité biologique
- Description
Chemical Information
Publications (1)
Pureté et documentation
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MCOPPB

ADL-5859 hydrochloride

Publications Citing Use of MedChemExpress (MCE) MCOPPB

Voir tous les produits spécifiques à Isoform Opioid Receptor

Activité biologique

Chemical Information

Publications (1)

Pureté et documentation

Références

Calculators

Help & FAQs

MCOPPB Related Classifications

HY-10886 Related Classifications

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