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Cat. No.: HY-171477

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Metahexestrol

Metahexestrol is an estrogen receptor (E2R) inhibitor with antitumor activity. It significantly inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cells (ED₅₀ = 1.0 μM). Additionally, Metahexestrol also exhibits inhibitory effects in estrogen receptor-negative MDA-MB-231 cells, and its antiproliferative activity cannot be reversed by estrogen, suggesting that its mechanism of action may be partially independent of the E2R pathway. Metahexestrol can be used in research on estrogen-dependent breast cancer.

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CAS No.: 71953-72-5
Formule: C₁₈H₂₂O₂
Masse moléculaire:270.37

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Metahexestrol Chemical Structure

CAS No.: 71953-72-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Estrogen Receptor/ERR :

Chemical Information

CAS No. 71953-72-5
Masse moléculaire 270.37
Formule C₁₈H₂₂O₂
SMILES

CC[C@H](C1=CC(O)=CC=C1)[C@H](C2=CC(O)=CC=C2)CC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hartmann R W, et al. Anti-proliferative effects of 1, 2-diphenylethane oestrogens and anti-oestrogens on human breast cancer cells[J]. Journal of cancer research and clinical oncology, 1985, 110(1): 17-24.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Metahexestrol

Voir tous les produits spécifiques à Isoform Estrogen Receptor/ERR

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Metahexestrol Related Classifications

HY-171477 Related Classifications

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