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Cat. No.: HY-156190

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NR2F2-IN-1

NR2F2-IN-1 (COUP-TFII inhibitor) is a small-molecule inhibitor targeting the orphan nuclear receptor COUP-TFII (NR2F2). NR2F2-IN-1 directly binds to the ligand-binding domain of COUP-TFII (NR2F2) and disrupts its interaction with transcriptional regulators including FOXA1. NR2F2-IN-1 induces anti-tumor activity in prostate cancer and can be used for prostate cancer research.

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CAS No.: 1049691-47-5
Formule: C₁₇H₂₀ClN₃O₂S
Masse moléculaire:365.88

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

NR2F2-IN-1 Chemical Structure

CAS No.: 1049691-47-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Chemical Information

CAS No. 1049691-47-5
Masse moléculaire 365.88
Formule C₁₇H₂₀ClN₃O₂S
SMILES

COC(C(OC)=C1)=CC=C1CCNC2=C3C=C(C)SC3=NC=N2.Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wang L, et al. Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment. Science advances. 2020 May;6(18):eaaz8031. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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