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Cat. No.: HY-N2980

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Ocotillone

Name: Ocotillone
Brand: MedChemExpress
SKU: HY-N2980
Availability: PreOrder

(Synonyms: Cabraleone)

Ocotillone ((24S)-20,24-Epoxy-25-hydroxydammaran-3-one) is a triterpenoids that can be isolated from the fruits of Dysoxylum richii. Ocotillone has antibacterial activities against P. aeruginosa and S. typhimurium without hemolytic activity.

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CAS No.: 35761-54-7
Formule: C₃₀H₅₀O₃
Masse moléculaire:458.72

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Ocotillone Chemical Structure

CAS No.: 35761-54-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
Col2	EC₅₀	>1 x 10³ nM Compound: cabraleone	Cytotoxicity against human Col2 cells Cytotoxicity against human Col2 cells	[PMID: 15043407]
COLO 205	IC₅₀	>100 μM Compound: 12	Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay	[PMID: 17346076]
HepG2	IC₅₀	142 μM Compound: 15, 24-epi-ocotillol	Cytotoxicity against human Hep G2 cells after 48 hrs by WST-8 assay Cytotoxicity against human Hep G2 cells after 48 hrs by WST-8 assay	[PMID: 15730243]
HUVEC	ED₅₀	>1 x 10³ nM Compound: cabraleone	Cytotoxicity against HUVEC Cytotoxicity against HUVEC	[PMID: 15043407]
K562	IC₅₀	>100 μM Compound: 12	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 17346076]
K562/Adr	IC₅₀	>100 μM Compound: 12	Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay	[PMID: 17346076]
K562/Adr	IC₅₀	>100 μM Compound: 12	Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay	[PMID: 17346076]
KB	ED₅₀	>1 x 10³ nM Compound: cabraleone	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 15043407]
KB	IC₅₀	>100 μM Compound: 12	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 17346076]
LNCaP	ED₅₀	>1 x 10³ nM Compound: cabraleone	Cytotoxicity against human LNCAP cells Cytotoxicity against human LNCAP cells	[PMID: 15043407]
Lu1	ED₅₀	>1 x 10³ nM Compound: cabraleone	Cytotoxicity against human Lu1 cells Cytotoxicity against human Lu1 cells	[PMID: 15043407]
MCF7	IC₅₀	>100 μM Compound: 12	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 17346076]
TERT-RPE1	ED₅₀	>1 x 10³ nM Compound: cabraleone	Cytotoxicity against human telomerase reverse transcriptase expressing human RPE1 cells Cytotoxicity against human telomerase reverse transcriptase expressing human RPE1 cells	[PMID: 15043407]
WI-38	IC₅₀	2.4 μM Compound: 15, 24-epi-ocotillol	Cytotoxicity against human WI 38 cells after 48 hrs by WST-8 assay Cytotoxicity against human WI 38 cells after 48 hrs by WST-8 assay	[PMID: 15730243]
WI-38 VA13	IC₅₀	199 μM Compound: 15, 24-epi-ocotillol	Cytotoxicity against human VA13 cells after 48 hrs by WST-8 assay Cytotoxicity against human VA13 cells after 48 hrs by WST-8 assay	[PMID: 15730243]

Chemical Information

CAS No. 35761-54-7
Masse moléculaire 458.72
Formule C₃₀H₅₀O₃
SMILES

C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]3([H])[C@]4(O[C@H](C(C)(O)C)CC4)C)C)([H])[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC1)C
Synonyms

Cabraleone
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
- Microorganisms
Bifidobacterium richum
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Bi Y, et al. Synthesis and Antibacterial Evaluation of Novel 3-Substituted Ocotillol-Type Derivatives as Leads. Molecules. 2017 Apr 7;22(4):590. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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