ONO-2570366
ONO-2570366 (Compound 11a) is an antagonist of the cysteinyl leukotriene receptors CysLT1R and CysLT2R (IC50 = 14 nM). ONO-2570366 inhibits the binding of LTD4asthma.
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- Formule: C30H30ClFN2O7
- Masse moléculaire:585.02
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
[1]|
CysLT2 14 nM (IC50) |
CysLT1 |
Chemical Information
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Masse moléculaire 585.02
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Formule C30H30ClFN2O7
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SMILES
O=C(O)[C@H]1OC2=C(C=CC=C2N(C1)CCCC(O)=O)NC(C3=CC=C(C=C3)OCCCCC4=CC(F)=CC=C4Cl)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ONO-2570366 Related Classifications
HY-176921 Related Classifications
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