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Cat. No.: HY-117598

OXFBD03

OXFBD03 serves as an inhibitor of the BRD4(1) protein, which belongs to the bromodomain and extra terminal domain bromodomain family.

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Please store the product under the recommended conditions in the Certificate of Analysis.

CAS No.: 1429129-71-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

OXFBD03 serves as an inhibitor of the BRD4(1) protein, which belongs to the bromodomain and extra terminal domain bromodomain family.

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Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>10 μM Compound: 9	Cytotoxicity against human A549 cells after 72 hrs by MTS assay Cytotoxicity against human A549 cells after 72 hrs by MTS assay	[PMID: 23517011]
HeLa	IC₅₀	>100 μM Compound: 9	Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay	[PMID: 23517011]
MV4-11	IC₅₀	0.616 μM Compound: 9	Cytotoxicity against human MV4-11 cells after 72 hrs by MTS assay Cytotoxicity against human MV4-11 cells after 72 hrs by MTS assay	[PMID: 23517011]
NCI-H1975	IC₅₀	>10 μM Compound: 9	Cytotoxicity against human NCI-H1975 cells after 72 hrs by MTS assay Cytotoxicity against human NCI-H1975 cells after 72 hrs by MTS assay	[PMID: 23517011]
U2OS	IC₅₀	>100 μM Compound: 9	Cytotoxicity against human U2OS cells after 24 hrs by WST-1 assay Cytotoxicity against human U2OS cells after 24 hrs by WST-1 assay	[PMID: 23517011]

CAS No. 1429129-71-4
Masse moléculaire 337.37
Formule C₂₀H₁₉NO₄
SMILES

OC(C1=CC=CC=C1)C2=CC(C3=C(C)ON=C3C)=CC(OC(C)=O)=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.