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Cat. No.: HY-137665

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PET-cGMP

PET-cGMP is a cyclic guanosine monophosphate analog and an effective selective agonist of PKG I, the EC₅₀ of PET-cGMP for PKG Iβ is 3.8 nM, while for PKG II, it's 193 nM.

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CAS No.: 78080-27-0
Formule: C₁₈H₁₆N₅O₇P
Masse moléculaire:445.32

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

PET-cGMP Chemical Structure

CAS No.: 78080-27-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

PET-cGMP is a cyclic guanosine monophosphate analog and an effective selective agonist of PKG I, the EC₅₀ of PET-cGMP for PKG Iβ is 3.8 nM, while for PKG II, it's 193 nM^[1].

Chemical Information

CAS No. 78080-27-0
Masse moléculaire 445.32
Formule C₁₈H₁₆N₅O₇P
SMILES

O=C1C2=C(NC3=NC(C4=CC=CC=C4)=CN13)N([C@]5([H])O[C@@](CO[P]6(O)=O)([H])[C@](O6)([H])[C@H]5O)C=N2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. James C Campbell, et al. Structural Basis of Analog Specificity in PKG I and II. ACS Chem Biol. 2017 Sep 15;12(9):2388-2398. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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