PF-06672131
Based on 1 Customer Validation
PF-06672131 is an alkynylated afatinib derivative and a small molecule probe that is reactive to cysteine. PF-06672131 is an inhibitor of epidermal growth factor receptor (EGFR) kinase that targets the ATP pockets of EGFR. PF-06672131 can be used for activity-based protein profiling studies.
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- Pureté: 99.47%
- CAS No.: 1621002-27-4
- Formule: C23H21ClFN5O2
- Masse moléculaire:453.90
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Chemical Information
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CAS No. 1621002-27-4
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Appearance Solid
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Masse moléculaire 453.90
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Formule C23H21ClFN5O2
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Color Off-white to light yellow
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SMILES
O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1OCC#C)/C=C/CN(C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : ≥ 100 mg/mL (220.31 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2031 mL | 11.0156 mL | 22.0313 mL | 55.0782 mL |
| 5 mM | 0.4406 mL | 2.2031 mL | 4.4063 mL | 11.0156 mL | |
| 10 mM | 0.2203 mL | 1.1016 mL | 2.2031 mL | 5.5078 mL | |
| 15 mM | 0.1469 mL | 0.7344 mL | 1.4688 mL | 3.6719 mL | |
| 20 mM | 0.1102 mL | 0.5508 mL | 1.1016 mL | 2.7539 mL | |
| 25 mM | 0.0881 mL | 0.4406 mL | 0.8813 mL | 2.2031 mL | |
| 30 mM | 0.0734 mL | 0.3672 mL | 0.7344 mL | 1.8359 mL | |
| 40 mM | 0.0551 mL | 0.2754 mL | 0.5508 mL | 1.3770 mL | |
| 50 mM | 0.0441 mL | 0.2203 mL | 0.4406 mL | 1.1016 mL | |
| 60 mM | 0.0367 mL | 0.1836 mL | 0.3672 mL | 0.9180 mL | |
| 80 mM | 0.0275 mL | 0.1377 mL | 0.2754 mL | 0.6885 mL | |
| 100 mM | 0.0220 mL | 0.1102 mL | 0.2203 mL | 0.5508 mL |
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