Ph-HTBA
Ph-HTBA is a high-affinity, brain-penetrating modulator for CaMKIIα. Ph-HTBA has binding affinity for CaMKIIα with a Kd value of 757 nM. Ph-HTBA can be used for the research of ischemia and neurodegenerative disorders.
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- CAS No.: 2368927-41-5
- Formule: C19H18O3
- Masse moléculaire:294.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Kd: 757 nM (CaMKIIα)[1]
Ph-HTBA can inhibit HOCPCA binding with a Ki value of 1.4 μM[1].
Ph-HTBA has binding affinity for CaMKIIα with a Kd value of 757 nM[1].
Ph-HTBA (compound 1i) has a marked hub thermal stabilization effect along with a distinct CaMKIIα Trp403 flip upon binding[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2368927-41-5
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Masse moléculaire 294.34
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Formule C19H18O3
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SMILES
O=C(O)/C=C1CCCC2=CC(C3=CC=CC=C3)=CC=C2C\1O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ph-HTBA Related Classifications
HY-151797 Related Classifications
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