Phenolic acid
Phenolic acid is an endogenous metabolite.
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- CAS No.: 29656-58-4
- Formule: C7H8D2O3
- Masse moléculaire:144.16
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | IC50 |
5 mM
Compound: salicylic acid
|
Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay
Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay
|
[PMID: 26617961] |
| DU-145 | IC50 |
>100 μM
Compound: 2; Salic
|
Antiproliferative activity against human DU-145 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human DU-145 cells incubated for 48 hrs by MTT assay
|
[PMID: 36257283] |
| HEK293 | IC50 |
>15 mM
Compound: Salicylate
|
Cytotoxicity against HEK293 cells harboring pendrin P123S mutant after 72 hrs by MTT assay
Cytotoxicity against HEK293 cells harboring pendrin P123S mutant after 72 hrs by MTT assay
|
[PMID: 28341401] |
| HT-29 | IC50 |
>100 μM
Compound: 2; Salic
|
Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay
|
[PMID: 36257283] |
| MCF7 | IC50 |
>100 μM
Compound: 2; Salic
|
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
|
[PMID: 36257283] |
| RAW264.7 | CC50 |
>40 μM
Compound: 1
|
Cytotoxicity against mouse RAW264.7 cells assessed as reduction in survival rate after 24 hrs by MTT assay
Cytotoxicity against mouse RAW264.7 cells assessed as reduction in survival rate after 24 hrs by MTT assay
|
[PMID: 25200306] |
| Sf9 | IC50 |
500 μM
Compound: salicylic acid
|
Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5 mins by HTRF assay
Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5 mins by HTRF assay
|
[PMID: 27046190] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 29656-58-4
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Masse moléculaire 144.16
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Formule C7H8D2O3
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SMILES
OC([2H])=O.[D1]O[H].C1=CC=CC=C1
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)