Triethylene glycol
Based on 1 Customer Validation
Triethylene glycol (PROTAC Linker 25) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- Pureté: 99.56%
- CAS No.: 112-27-6
- Formule: C6H14O4
- Masse moléculaire:150.17
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Stockage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform PROTAC Linkers
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Activité biologique
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 112-27-6
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Appearance Liquid (Density: 1.124 g/cm3)
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Masse moléculaire 150.17
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Formule C6H14O4
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Color Colorless to light yellow
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SMILES
OCCOCCOCCO
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Synonyms
PROTAC Linker 25
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
H2O : 100 mg/mL (665.91 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (665.91 mM); Clear solution; Need ultrasonic
Pureté et documentation
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Fiche technique (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.6591 mL | 33.2956 mL | 66.5912 mL | 166.4780 mL |
| 5 mM | 1.3318 mL | 6.6591 mL | 13.3182 mL | 33.2956 mL | |
| 10 mM | 0.6659 mL | 3.3296 mL | 6.6591 mL | 16.6478 mL | |
| 15 mM | 0.4439 mL | 2.2197 mL | 4.4394 mL | 11.0985 mL | |
| 20 mM | 0.3330 mL | 1.6648 mL | 3.3296 mL | 8.3239 mL | |
| 25 mM | 0.2664 mL | 1.3318 mL | 2.6636 mL | 6.6591 mL | |
| 30 mM | 0.2220 mL | 1.1099 mL | 2.2197 mL | 5.5493 mL | |
| 40 mM | 0.1665 mL | 0.8324 mL | 1.6648 mL | 4.1619 mL | |
| 50 mM | 0.1332 mL | 0.6659 mL | 1.3318 mL | 3.3296 mL | |
| 60 mM | 0.1110 mL | 0.5549 mL | 1.1099 mL | 2.7746 mL | |
| 80 mM | 0.0832 mL | 0.4162 mL | 0.8324 mL | 2.0810 mL | |
| 100 mM | 0.0666 mL | 0.3330 mL | 0.6659 mL | 1.6648 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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