CD133
CD133 (prominin-1) is a five-transmembrane pentaspan glycoprotein whose extracellular domains concentrate in membrane protrusions, and whose AC133 epitope has defined CD133-positive stem populations since the 1990s. It marks hematopoietic stem and progenitor cells, endothelial progenitors and neural stem cells, and in cancer biology it labels tumor-initiating cells of glioma, colon and pancreatic carcinoma. CD133 is released in exosomes, and its expression correlates with stem-like properties and therapy resistance in several malignancies. Recombinant CD133 is a standard reagent for stem cell enrichment and cancer stem cell research. CD133 concentrates in cholesterol-rich lipid rafts of membrane protrusions.
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CD133 Protéines Recombinantes (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formule: Human
- Masse moléculaire: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
