(±)8(9)-EET
(±)8(9)-EET is one of the main metabolites produced by the metabolism of arachidonic acid (HY-109590) through the cytochrome P450 epoxide pathway. (±)8(9)-EET is an effective substrate for COX-1 and COX-2. (±)8(9)-EET activates PPARα in HEK293 cells and inhibits the activity of NF-κB induced by IL-1β in a PPARα-dependent and -independent manner. The (8S,9R)-isomer of (±)8(9)-EET ([(8S,9R)-EET]) causes vasoconstriction, thereby reducing renal plasma flow and glomerular filtration rate.
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- CAS No.: 184488-44-6
- Formule: C20H32O3
- Masse moléculaire:320.47
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Stockage:
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 184488-44-6
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Masse moléculaire 320.47
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Formule C20H32O3
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SMILES
CCCCC/C=C\C/C=C\CC1OC1C/C=C\CCCC(O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(±)8(9)-EET Related Classifications
HY-179488 Related Classifications
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