RWJ-58643
RWJ-58643 is a β-trypsin inhibitor that suppresses allergic inflammation. RWJ-58643 (100 mg) significantly reduced nasal allergy symptoms, eosinophil infiltration, and IL-5 levels at low doses. RWJ-58643 resulted in late eosinophilia and elevated IL-5 levels at high doses (300 mg and 600 mg). RWJ-58643 modulates allergic responses by inhibiting the release of β-trypsin from mast cells.
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- CAS No.: 287183-00-0
- Formule: C20H26N6O4S
- Masse moléculaire:446.52
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Activité biologique
Chemical Information
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CAS No. 287183-00-0
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Masse moléculaire 446.52
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Formule C20H26N6O4S
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SMILES
O=C([C@H]1N(C(C)=O)C[C@H](O)C1)NC(C(C2=NC3=CC=CC=C3S2)=O)CCCNC(N)=N
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RWJ-58643 Related Classifications
HY-19472 Related Classifications
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