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Cat. No.: HY-175535

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SRI-32743

SRI-32743 is an allosteric human dopamine transporter (hDAT) modulator (IC₅₀=9.86 μM). SRI-32743 is promising for research of HIV-Tat-induced neurotoxicity.

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CAS No.: 1940118-42-2
Formule: C₂₆H₂₅N₅
Masse moléculaire:407.51

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

SRI-32743 Chemical Structure

CAS No.: 1940118-42-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

SRI-32743 is an allosteric human dopamine transporter (hDAT) modulator (IC₅₀=9.86 μM). SRI-32743 is promising for research of HIV-Tat-induced neurotoxicity^[1].

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Chemical Information

CAS No. 1940118-42-2
Masse moléculaire 407.51
Formule C₂₆H₂₅N₅
SMILES

CCC(CNC1=NC(C(C(C)=C2)=CN3C2=NC=C3)=NC4=CC=CC=C14)C5=CC=CC=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. N-(2-phenylbutyl)-5,6,7,8-tetrahydro-quinazolin-4-amines as allosteric modulators of HIV-DAT-tat interaction. Bioorg Med Chem Lett. 2025 Dec 1;128:130345. [Content Brief]

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Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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SRI-32743

Voir tous les produits spécifiques à Isoform HIV

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

SRI-32743 Related Classifications

HY-175535 Related Classifications

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