VGN50
VGN50 is a bioactive molecule that mimics the function of K-Rta and down-regulates MYC-mediated gene transcription. VGN50 has antitumor activity.
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- Formule: C121H218N46O32
- Masse moléculaire:2829.31
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
VGN50 (24 μM, 24 h) Down-regulates the expression of MYC in BCBL-1 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:PEL xenograft mouse model[1]
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Dosage:10 mg/kg
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Administration:i.p., for 10 consecutive days
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Result:Ascites containing tumors accumulate without weight gain.
Chemical Information
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Masse moléculaire 2829.31
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Formule C121H218N46O32
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Sequence
{d-Arg}-Lys-Lys-Arg-Arg-{Orn}-Arg-Arg-Arg-{βAla}-Leu-Ser-Ser-Ile-Leu-Gln-Gly-Leu-Tyr-Gln-Leu-Asp-Thr
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Sequence Shortening
{d-Arg}-KKRR-{Orn}-RRR-{βAla}-LSSILQGLYQLDT
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)