CAII/lX-IN-2
CAII/lX-IN-2 is a carbonic anhydrase inhibitor with an IC50 of 2.2 nM against hCA IX and 19.8 nM against hCA XII. CAII/lX-IN-2 inhibits the catalytic activities of cytosolic hCA I, hCA II, and transmembrane tumor-associated hCA IX and hCA XII in a concentration-dependent manner. CAII/lX-IN-2 can be used in research related to metastatic solid tumors.
For research use only. We do not sell to patients.
- CAS No.: 104-22-3
- Formula: C13H14N2O2S
- Molecular Weight:262.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hCA I 20.0 nM (IC50) |
hCA II 1.7 nM (IC50) |
hCA IX 2.2 nM (IC50) |
hCA XII 19.8 nM (IC50) |
CAII/IX-IN-2 (compound 3i) potently inhibits recombinant human hCA I (Ki = 20.0 nM), hCA II (Ki = 1.7 nM), hCA IX (Ki = 2.2 nM) and hCA XII (Ki = 19.8 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 104-22-3
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Molecular Weight 262.33
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Formula C13H14N2O2S
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SMILES
O=S(N)(C1=CC=C(NCC2=CC=CC=C2)C=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CAII/lX-IN-2 Related Classifications
HY-184038 Related Classifications
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