CAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is the inhibitor for carbonic anhydrase (CA) that binds CA IX, CA XII and CA II with Ki of 1.324 μM, 0.435 μM and 3.035 μM. CAIX/CAXII-IN-4 exhibits board-spectrum antitumor efficacy, inhibits the proliferation of CNS cancer U251 with GI50 of 0.361 μM.
For research use only. We do not sell to patients.
- Formula: C23H21N5O3S
- Molecular Weight:447.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CA XII 0.435 μM (Ki) |
CA IX 1.324 μM (Ki) |
CA Ⅱ 3.035 μM (Ki) |
Chemical Information
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Molecular Weight 447.51
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Formula C23H21N5O3S
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SMILES
CC1=CC(C)=CC(C(NC2=CC=CC(C3=CN(C4=CC=C(S(=O)(N)=O)C=C4)N=N3)=C2)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)