CAIX-IN-17
CAIX-IN-17 is a carbonic anhydrase IX (CAIX) inhibitor with an IC50 of 61 nM and accumulates specifically in CAIX-expressing xenograft tumors. CAIX-IN-17 can be labeled with 68Ga and acts as a CAIX-targeted PET tracer for detection of clear-cell renal cell carcinoma.
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- 화학식: C21H36N8O10S2
- 분자량:624.69
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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CA IX 61 nM (IC50) |
CAIX-IN-17 (Compound 14) inhibits recombinant human CAIX with an IC50 of 61 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 624.69
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화학식 C21H36N8O10S2
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SMILES
O=C(NC1=NN=C(S(=O)(N)=O)S1)CCOCCOCCNC(CN2CCN(CC(O)=O)CCN(CC(O)=O)CC2)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CAIX-IN-17 Related Classifications
HY-181112 Related Classifications
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