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Cat. No.: HY-44745

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Camptothecin impurity 1

Name: Camptothecin impurity 1
Brand: MedChemExpress
SKU: HY-44745
Price: 115.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Camptothecin impurity 1 (Compound 1) is an impurity of Camptothecin (HY-16560), which serves as a starting compound for the synthesis of tricyclic intermediates of Camptothecin.

For research use only. We do not sell to patients.

Purity: 99.95%
CAS No.: 127318-97-2
Formula: C₁₅H₁₇NO₅
Molecular Weight:291.30

Storage:

Store at room temperature, keep dry and cool.

In solvent -80°C, 1 year , -20°C, 6 months

Camptothecin impurity 1 Chemical Structure

CAS No.: 127318-97-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Camptothecin impurity 1 (Compound 1) is an impurity of Camptothecin (HY-16560), which serves as a starting compound for the synthesis of tricyclic intermediates of Camptothecin^[1].

In Vitro

Camptothecin (CPT), an alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC₅₀ value of 679 nM. Camptothecin (CPT) exerts potent antitumor activity against colorectal cancer, breast cancer, lung cancer and ovarian cancer, and regulates HIF-1α activity by altering the miRNA expression pattern in human cancer cells.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 127318-97-2
Appearance Solid
Molecular Weight 291.30
Formula C₁₅H₁₇NO₅
Color Light yellow to yellow
SMILES

O=C1C(CC)C(C=C23)=C(CO1)C(N2CCC43OCCO4)=O
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent	-80°C	1 year
	-20°C	6 months

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu, et al. A method for preparing and purifying a camptothecin tricyclic intermediate. CN120097997A.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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