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United States

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Cat. No.: HY-P10805

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Capsid assembly inhibitor

Capsid assembly inhibitor is a 12-mer peptide that binds the capsid (CA) domain of Gag and inhibits assembly of immature- and mature-like HIV-1 capsid particles in vitro.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 865292-94-0
화학식: C₆₉H₉₆N₁₂O₂₂
분자량:1445.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Capsid assembly inhibitor Chemical Structure

CAS No.: 865292-94-0

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Capsid assembly inhibitor is a 12-mer peptide that binds the capsid (CA) domain of Gag and inhibits assembly of immature- and mature-like HIV-1 capsid particles in vitro^[1].

All HIV Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
MT2	CC₅₀	>135 μM Compound: CAI	Cytotoxicity against human MT2 cells after 4 days by XTT assay Cytotoxicity against human MT2 cells after 4 days by XTT assay	[PMID: 24613163]
MT2	IC₅₀	>135 μM Compound: CAI	Antiviral activity against HIV-1 3B infected in human MT-2 cells assessed as reduction in p24 antigen level incubated for overnight measured on fourth day post infection by multi-cycle infection assay based sandwich ELISA Antiviral activity against HIV-1 3B infected in human MT-2 cells assessed as reduction in p24 antigen level incubated for overnight measured on fourth day post infection by multi-cycle infection assay based sandwich ELISA	[PMID: 24613163]
TZM	CC₅₀	>135 μM Compound: CAI	Cytotoxicity against human TZM-bl cells after 3 days by XTT assay Cytotoxicity against human TZM-bl cells after 3 days by XTT assay	[PMID: 24613163]

Chemical Information

CAS No. 865292-94-0
분자량 1445.57
화학식 C₆₉H₉₆N₁₂O₂₂
Sequence

Ile-Thr-Phe-Glu-Asp-Leu-Leu-Asp-Tyr-Tyr-Gly-Pro
Sequence Shortening

ITFEDLLDYYGP
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sticht J, et al. A peptide inhibitor of HIV-1 assembly in vitro. Nat Struct Mol Biol. 2005 Aug;12(8):671-7. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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