Capsid assembly inhibitor
Capsid assembly inhibitor is a 12-mer peptide that binds the capsid (CA) domain of Gag and inhibits assembly of immature- and mature-like HIV-1 capsid particles in vitro.
For research use only. We do not sell to patients.
- CAS No.: 865292-94-0
- Formula: C69H96N12O22
- Molecular Weight:1445.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MT2 | CC50 |
>135 μM
Compound: CAI
|
Cytotoxicity against human MT2 cells after 4 days by XTT assay
Cytotoxicity against human MT2 cells after 4 days by XTT assay
|
[PMID: 24613163] |
| MT2 | IC50 |
>135 μM
Compound: CAI
|
Antiviral activity against HIV-1 3B infected in human MT-2 cells assessed as reduction in p24 antigen level incubated for overnight measured on fourth day post infection by multi-cycle infection assay based sandwich ELISA
Antiviral activity against HIV-1 3B infected in human MT-2 cells assessed as reduction in p24 antigen level incubated for overnight measured on fourth day post infection by multi-cycle infection assay based sandwich ELISA
|
[PMID: 24613163] |
| TZM | CC50 |
>135 μM
Compound: CAI
|
Cytotoxicity against human TZM-bl cells after 3 days by XTT assay
Cytotoxicity against human TZM-bl cells after 3 days by XTT assay
|
[PMID: 24613163] |
Chemical Information
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CAS No. 865292-94-0
-
Molecular Weight 1445.57
-
Formula C69H96N12O22
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Sequence
Ile-Thr-Phe-Glu-Asp-Leu-Leu-Asp-Tyr-Tyr-Gly-Pro
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Sequence Shortening
ITFEDLLDYYGP
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)