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製品番号: HY-P10805

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Capsid assembly inhibitor

Capsid assembly inhibitor is a 12-mer peptide that binds the capsid (CA) domain of Gag and inhibits assembly of immature- and mature-like HIV-1 capsid particles in vitro.

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CAS 番号: 865292-94-0
分子式: C₆₉H₉₆N₁₂O₂₂
分子量:1445.57

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Capsid assembly inhibitor 構造式

CAS 番号: 865292-94-0

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Capsid assembly inhibitor is a 12-mer peptide that binds the capsid (CA) domain of Gag and inhibits assembly of immature- and mature-like HIV-1 capsid particles in vitro^[1].

HIV アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
MT2	CC₅₀	>135 μM Compound: CAI	Cytotoxicity against human MT2 cells after 4 days by XTT assay Cytotoxicity against human MT2 cells after 4 days by XTT assay	[PMID: 24613163]
MT2	IC₅₀	>135 μM Compound: CAI	Antiviral activity against HIV-1 3B infected in human MT-2 cells assessed as reduction in p24 antigen level incubated for overnight measured on fourth day post infection by multi-cycle infection assay based sandwich ELISA Antiviral activity against HIV-1 3B infected in human MT-2 cells assessed as reduction in p24 antigen level incubated for overnight measured on fourth day post infection by multi-cycle infection assay based sandwich ELISA	[PMID: 24613163]
TZM	CC₅₀	>135 μM Compound: CAI	Cytotoxicity against human TZM-bl cells after 3 days by XTT assay Cytotoxicity against human TZM-bl cells after 3 days by XTT assay	[PMID: 24613163]

化学情報

CAS 番号 865292-94-0
分子量 1445.57
分子式 C₆₉H₉₆N₁₂O₂₂
配列

Ile-Thr-Phe-Glu-Asp-Leu-Leu-Asp-Tyr-Tyr-Gly-Pro
シーケンスの短縮

ITFEDLLDYYGP
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (257 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Sticht J, et al. A peptide inhibitor of HIV-1 assembly in vitro. Nat Struct Mol Biol. 2005 Aug;12(8):671-7. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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