110429-45-3
110429-45-3
Chemical Structure
m-PEG4-Br
- CAS No.: 110429-45-3
- Formula:C9H19BrO4
- Molecular Weight:271.15
IUPAC Name: 13-bromo-2,5,8,11-tetraoxatridecane
InChIKey: YFFFQGXWMHAJPP-UHFFFAOYSA-N
SMILES: COCCOCCOCCOCCBr
Biological Activity: m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency[1]. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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m-PEG4-Br | 96.34% | m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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References
Keywords
