112-12-9
112-12-9
Chemical Structure
2-Undecanone
- CAS No.: 112-12-9
- Formula:C11H22O
- Molecular Weight:170.30
IUPAC Name: undecan-2-one
InChIKey: KYWIYKKSMDLRDC-UHFFFAOYSA-N
SMILES: CC(CCCCCCCCC)=O
Biological Activity: 2-Undecanone is an orally active organic ketone. 2-Undecanone exerts antibacterial effects by inhibiting bacterial chaperone systems and interfering with the refolding of heat-inactivated proteins. 2-Undecanone also ameliorates asthmatic inflammation and airway remodeling by blocking the NF-κB pathway, and activates the Nrf2 pathway to reduce oxidative damage and prevent lung cancer induced by Benzo[a]pyrene (HY-107377). 2-Undecanone can be used in research related to cancer, asthma and infections[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Undecanone | 99.91% | 2-Undecanone is an orally active organic ketone. 2-Undecanone exerts antibacterial effects by inhibiting bacterial chaperone systems and interfering with the refolding of heat-inactivated proteins. 2-Undecanone also ameliorates asthmatic inflammation and airway remodeling by blocking the NF-κB pathway, and activates the Nrf2 pathway to reduce oxidative damage and prevent lung cancer induced by Benzo[a]pyrene (HY-107377). 2-Undecanone can be used in research related to cancer, asthma and infections. | ||||||||||||||||||||
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2-Undecanone (Standard) | ≥98% | 2-Undecanone (Standard) is the analytical standard of 2-Undecanone (HY-W016969). This product is intended for research and analytical applications. 2-Undecanone is an orally active organic ketone. 2-Undecanone exerts antibacterial effects by inhibiting bacterial chaperone systems and interfering with the refolding of heat-inactivated proteins. 2-Undecanone also ameliorates asthmatic inflammation and airway remodeling by blocking the NF-κB pathway, and activates the Nrf2 pathway to reduce oxidative damage and prevent lung cancer induced by Benzo[a]pyrene (HY-107377). 2-Undecanone can be used in research related to cancer, asthma and infections. | ||||||||||||||||||||
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2-Undecanone-d5 | 2-Undecanone-d5 is the deuterium labeled 2-Undecanone (HY-W016969). 2-Undecanone is an orally active organic ketone. 2-Undecanone exerts antibacterial effects by inhibiting bacterial chaperone systems and interfering with the refolding of heat-inactivated proteins. 2-Undecanone also ameliorates asthmatic inflammation and airway remodeling by blocking the NF-κB pathway, and activates the Nrf2 pathway to reduce oxidative damage and prevent lung cancer induced by Benzo[a]pyrene (HY-107377). 2-Undecanone can be used in research related to cancer, asthma and infections. | |||||||||||||||||||||
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Decanamide | Decanamide is a primary fatty amide. | |||||||||||||||||||||
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2-Tridecanone (Standard) | ≥98% | 2-Tridecanone, a nonalkaloid insecticide, is isolated from the wild tomato Lycopersicon hirsutum f. glabratum. 2-Tridecanone is a volatile organic compound. | ||||||||||||||||||||
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2-Decanone | 98.15% | 2-Decanone is an antifungal agent. 2-Decanone inhibits pathogen mycelial growth, spore germination, and appressorium formation. 2-Decanone downregulates spore germination-related genes (MfBmp1) and penetration structure formation genes (MfPls1), inducing reactive oxygen species (ROS) accumulation to trigger mitochondrial damage and subsequent spore apoptosis. 2-Decanone is promising for research of postharvest disease control in fruits and vegetables. | ||||||||||||||||||||
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2-Octanone (Standard) | ≥98% | 2-Octanone (n-Hexyl methyl ketone) (Standard) is the analytical standard of 2-Octanone (HY-W010409). This product is intended for research and analytical applications. 2-Octanone is a Flavonoids product that can be isolated from the herbs of Hydrangea macrophylla. | ||||||||||||||||||||
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Decanoic acid (Standard) | 99.76% | Decanoic acid (Standard) is the analytical standard of Decanoic acid. This product is intended for research and analytical applications. Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy. | ||||||||||||||||||||
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Decanoyl chloride | Decanoyl chloride is an organic compound belonging to the class of acid chlorides. It is a colorless liquid with a pungent odor and is commonly used as a reagent in various organic chemical reactions, especially in the synthesis of esters, amides and fatty acids. Decanoyl chloride has numerous applications in synthetic organic chemistry, especially in the production of pharmaceuticals, agrochemicals and specialty chemicals. In addition, it can be used as a precursor for the synthesis of surfactants and detergents. | |||||||||||||||||||||
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6-Undecanone | 99.32% | 6-Undecanone is a ligand of Odorant-binding protein 22 (OBP22) with a weak bind capacity. -Undecanone can be used as a negative control for Aedes aegypti mosquito infection research. | ||||||||||||||||||||
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Decanoic acid-13C | 98.0% | Decanoic acid-13C is the 13C-labeled Decanoic acid (HY-W015309). Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy. | ||||||||||||||||||||
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2-Dodecanone | 99.92% | 2-Dodecanone is an insecticide with repellent activity against specific insect species. 2-Dodecanone exhibits contact toxicity against adult Tribolium castaneum, Lasioderma serricorne and Liposcelis bostrychophila. 2-Dodecanone shows repellent effects against adult Lasioderma serricorne. | ||||||||||||||||||||
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2-Nonanone | 99.82% | 2-Nonanone is a ketone compound that inhibits the DnaKJE-ClpB bichaperone de-pendent refolding of heat-inactivated bacterial luciferases. 2-Nonanone interacts with hydrophobic segments of heat-inactivated substrates, and competes with chaperones IbpAB. 2-Nonanone can be used for the research of infection. | ||||||||||||||||||||
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References
- [1]. Lou Y, et al. Houttuynia cordata Thunb. and its bioactive compound 2-undecanone significantly suppress benzo(a)pyrene-induced lung tumorigenesis by activating the Nrf2-HO-1/NQO-1 signaling pathway. J Exp Clin Cancer Res. 2019;38(1):242. Published 2019 Jun 7. [Content Brief]
- [2]. Melkina OE, et al. Ketones 2-heptanone, 2-nonanone, and 2-undecanone inhibit DnaK-dependent refolding of heat-inactivated bacterial luciferases in Escherichia coli cells lacking small chaperon IbpB. Appl Microbiol Biotechnol. 2017;101(14):5765-5771. [Content Brief]
- [3]. Song G, et al. 2-Undecanone alleviates asthma by inhibiting NF-κB pathway. Biochem Cell Biol. 2023;101(1):101-111. [Content Brief]
