1121-89-7
1121-89-7
Chemical Structure
Glutarimide
- CAS No.: 1121-89-7
- Formula:C5H7NO2
- Molecular Weight:113.11
IUPAC Name: piperidine-2,6-dione
InChIKey: KNCYXPMJDCCGSJ-UHFFFAOYSA-N
SMILES: O=C(CCC1)NC1=O
Biological Activity: Glutarimide is a CRBN binder. Glutarimide exerts its function by binding to the thalidomide-binding domain of the CRBN protein. Glutarimide serves as an important structural component of many biologically active compounds. Glutarimide can be used in studies related to anemia, multiple myeloma and cycloheximide[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Glutarimide | 98.0% | Glutarimide is a CRBN binder. Glutarimide exerts its function by binding to the thalidomide-binding domain of the CRBN protein. Glutarimide serves as an important structural component of many biologically active compounds. Glutarimide can be used in studies related to anemia, multiple myeloma and cycloheximide. | ||||||||||||||||||||
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References
- [1]. Szewczyk SM, et al. Trends in Neosubstrate Degradation by Cereblon-Based Molecular Glues and the Development of Novel Multiparameter Optimization Scores. J Med Chem. 2024 Jan 25;67(2):1327-1335. [Content Brief]
- [2]. Nakae K, et al. Migrastatin acts as a muscarinic acetylcholine receptor antagonist. The Journal of antibiotics. 2006 Nov;59(11):685-92. [Content Brief]
Keywords
