14992-62-2
14992-62-2
Chemical Structure
Acetylcarnitine
- CAS No.: 14992-62-2
- Formula:C9H17NO4
- Molecular Weight:203.24
IUPAC Name: 3-acetoxy-4-(trimethylammonio)butanoate
InChIKey: RDHQFKQIGNGIED-UHFFFAOYSA-N
SMILES: C[N+](C)(C)CC(OC(C)=O)CC([O-])=O
Biological Activity: Acetylcarnitine is a CNS-penetrant endogenous metabolite. Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis. Acetylcarnitine attenuates oxidative stress and neuroinflammation. Acetylcarnitine can be used for fatigue-associated diseases research. Acetylcarnitine can be used as a candidate diagnostic and prognostic biomarker of hepatocellular carcinoma[1][2][3].
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Acetylcarnitine | 98.0% | Acetylcarnitine is a CNS-penetrant endogenous metabolite. Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis. Acetylcarnitine attenuates oxidative stress and neuroinflammation. Acetylcarnitine can be used for fatigue-associated diseases research. Acetylcarnitine can be used as a candidate diagnostic and prognostic biomarker of hepatocellular carcinoma. | ||||||||||||||||||||
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Acetylcarnitine (Standard) | ≥98% | Acetylcarnitine (Standard) is the analytical standard of Acetylcarnitine. This product is intended for research and analytical applications. Acetylcarnitine is an endogenous metabolite. | ||||||||||||||||||||
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Acetylcarnitine-d3 | Acetylcarnitine-d3 is the deuterium labeled Acetylcarnitine (HY-126358). Acetylcarnitine is an endogenous metabolite. | |||||||||||||||||||||
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References
- [1]. Helbing DL, et al. Conceptual foundations of acetylcarnitine supplementation in neuropsychiatric long COVID syndrome: a narrative review. Eur Arch Psychiatry Clin Neurosci. 2024 Dec;274(8):1829-1845. [Content Brief]
- [2]. Izzo LT, et al. Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis. Sci Adv. 2023 May 3;9(18):eadf0115. [Content Brief]
- [3]. Lu Y, et al. Acetylcarnitine Is a Candidate Diagnostic and Prognostic Biomarker of Hepatocellular Carcinoma. Cancer Res. 2016 May 15;76(10):2912-20. [Content Brief]
