17472-50-3
Chemical Structure
Cyclanoline chloride
- CAS No.: 17472-50-3
- Formula:C20H24ClNO4
- Molecular Weight:377.86
IUPAC Name: (7S,13aS)-2,9-dihydroxy-3,10-dimethoxy-7-methyl-5,6,7,8,13,13a-hexahydroisoquinolino[3,2-a]isoquinolin-7-ium chloride
InChIKey: RXPKBYHISSKVLV-ZOEDVAEJSA-N
SMILES: C[N@@+]12CCC3=CC(OC)=C(O)C=C3[C@]1([H])CC4=CC=C(OC)C(O)=C4C2.[Cl-]
Biological Activity: Cyclanoline chloride is an alkaloid. Cyclanoline chloride can be isolated from Fangji. Cyclanoline (chloride) inhibits the phosphorylation of JAK2 and STAT3, and induces Apoptosis. Cyclanoline chloride suppresses tumor growth in subcutaneous bladder cancer xenograft models of nude mice. Cyclanoline chloride reverses cisplatin resistance in bladder cancer cells and enhances the efficacy of Cisplatin (HY-17394). Cyclanoline chloride can be used for research related to bladder cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Cyclanoline chloride | 96.27% | Cyclanoline chloride is an alkaloid. Cyclanoline chloride can be isolated from Fangji. Cyclanoline (chloride) inhibits the phosphorylation of JAK2 and STAT3, and induces Apoptosis. Cyclanoline chloride suppresses tumor growth in subcutaneous bladder cancer xenograft models of nude mice. Cyclanoline chloride reverses cisplatin resistance in bladder cancer cells and enhances the efficacy of Cisplatin (HY-17394). Cyclanoline chloride can be used for research related to bladder cancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.81
HY-N13341N-Methylcorydalminechloride -
Similarity Score 0.81
HY-N0735Phellodendrine chloride -
Similarity Score 0.80
HY-N0427Phellodendrine -
Similarity Score 0.78
HY-N1255AScoulerine hydrochloride -
Similarity Score 0.78
HY-N1255Scoulerine -
Similarity Score 0.74
HY-172013N-Methylcanadium iodide -
Similarity Score 0.72
HY-N0927(-)-Isocorypalmine -
Similarity Score 0.72
HY-N0927A(+)-Isocorypalmine -
Similarity Score 0.72
HY-N12063Tetrahydropalmatrubine -
Explore the MedChemAI to find more analogs
