1809581-87-0
1809581-87-0
Chemical Structure
MM-206
- CAS No.: 1809581-87-0
- Formula:C22H12F5NO3S2
- Molecular Weight:497.46
IUPAC Name: 2,3,4,5,6-pentafluoro-N-(4-hydroxy-3-(phenylthio)naphthalen-1-yl)benzenesulfonamide
InChIKey: ZXJHEANDHXHGMV-UHFFFAOYSA-N
SMILES: O=S(C1=C(C(F)=C(C(F)=C1F)F)F)(NC2=C3C=CC=CC3=C(C(SC4=CC=CC=C4)=C2)O)=O
Biological Activity: MM-206, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines[1].
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MM-206 | 99.9% | MM-206, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines. | ||||||||||||||||||||
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