1821908-48-8
1821908-48-8
Chemical Structure
SGC2085
- No. CAS: 1821908-48-8
- Formula:C19H24N2O2
- Molecular Weight:312.41
IUPAC Name: (S)-2-amino-N-(4-(3,5-dimethylphenoxy)-3-methylbenzyl)propanamide
InChIKey: GLFOFXKMALJTCZ-HNNXBMFYSA-N
SMILES: CC1=CC(OC2=CC=C(CNC([C@@H](N)C)=O)C=C2C)=CC(C)=C1
Biological Activity: SGC2085 is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM. SGC2085 also selectively inhibits PRMT6 with an IC50 value of 5.2 μM, but not other PRMT proteins[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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SGC2085 | 99.46% | SGC2085 is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM. SGC2085 also selectively inhibits PRMT6 with an IC50 value of 5.2 μM, but not other PRMT proteins. | ||||||||||||||||||||
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SGC2085 (Standard) | ≥98% | SGC2085 (Standard) is the analytical standard of SGC2085 (HY-100565). This product is intended for research and analytical applications. SGC2085 is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM. SGC2085 also selectively inhibits PRMT6 with an IC50 value of 5.2 μM, but not other PRMT proteins. | ||||||||||||||||||||
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SGC2085 hydrochloride | SGC2085 hydrochloride is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM. SGC2085 hydrochloride also selectively inhibits PRMT6 with an IC50 value of 5.2 μM, but not other PRMT proteins. | |||||||||||||||||||||
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LY2048978 | LY2048978 is a non-selective opioid receptor antagonist with Ki of 0.287, 0.471 and 1.05 nM for human mu, kappa and delta opioid receptors in vitro, respectively. LY2048978 can be used in the research of major depressive disorder and alcohol use disorder. | |||||||||||||||||||||
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(R)-Safinamide | 99.89% | (R)-Safinamide (FCE 28073) is the enantiomer of Safinamide (HY-70057). (R)-Safinamide is an orally active, alanine-derived monoamine oxidase inhibitor with an IC50 of 1.77 μM for rat MAO-B and an IC50 of 50 μM for rat MAO-A. (R)-Safinamide regulates the activity of monoamine oxidase isoforms in brain homogenates. (R)-Safinamide is used in epilepsy research. | ||||||||||||||||||||
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NDH-1 inhibitor-1 | 99.78% | NDH-1 inhibitor-1 is a NADH-ubiquinone oxidoreductase (NDH-1) inhibitor with a pIC50 of 5.40 in potato tuber mitochondria and a pIC50 of 6.15 in Escherichia coli cell membranes. NDH-1 inhibitor-1 acts on the ubiquinone catalytic site to inhibit enzyme activity. NDH-1 inhibitor-1 can be used to study pathogenic microbial infections or mitochondrial diseases. | ||||||||||||||||||||
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Safinamide (Standard) | ≥98% | Safinamide (Standard) is the analytical standard of Safinamide. This product is intended for research and analytical applications. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 µM). Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 µM) than at resting (IC50=262 µM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al. | ||||||||||||||||||||
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Diorcinol | 99.30% | Diorcinol is a potent SHP1 inhibitor with an IC50 value of 0.96 μM. Diorcinol can be isolated from Aspergillus sydowii. Diorcinol has good blood-brain barrier penetration and can be used for diabetes research. | ||||||||||||||||||||
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Diorcinol D | Diorcinol D is a natural product with antifungal activity. Diorcinol D inhibits CYP51 expression, reduces Cdr1 expression, blocks efflux pump activity, and impedes ergosterol biosynthesis. It inhibits planktonic and biofilm growth of Candida albicans. Diorcinol D is applicable to research related to fungal infections. | |||||||||||||||||||||
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Verticilatin | Verticilatin is a prenylated diaryl ether derived from phytopathogenic fungi, acting as an antibacterial agent and biofilm inhibitor. Verticilatin exhibits no direct growth inhibitory activity against Gram-negative bacteria. Verticilatin effectively inhibits the growth of Gram-positive strains, including methicillin-sensitive/resistant Staphylococcus aureus and Enterococcus faecalis, and reduces the biofilm-forming ability of Gram-negative Stenotrophomonas maltophilia. Verticilatin can be used for infections caused by the aforementioned Gram-positive bacteria and biofilm infections caused by Stenotrophomonas maltophilia. | |||||||||||||||||||||
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Cyperin | Cyperine is a phytotoxic fungal metabolite that has been found in A. cypericola. It inhibits A. thaliana enoyl-acyl carrier protein reductase (ENR; IC50=89 μM). Cyperine induces necrosis in a panel of nine plant species in a leaf bioassay and inhibits root growth in A. thaliana seedlings (IC50=38.4 μM). | |||||||||||||||||||||
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5-(2-Carboxyphenoxy)isophthalic acid | 5-(2-Carboxyphenoxy)isophthalic acid (5-(2'-Carboxylphenoxy)isophthalic acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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