1875-50-9
1875-50-9
Chemical Structure
(Rac)-Rasagiline
Synonym(s): AGN1135; (Rac)-TVP1012
- CAS No.: 1875-50-9
- Formula:C12H13N
- Molecular Weight:171.24
IUPAC Name: N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine
InChIKey: RUOKEQAAGRXIBM-UHFFFAOYSA-N
SMILES: C#CCNC1CCC2=C1C=CC=C2
Biological Activity: (Rac)-Rasagiline (AGN1135) is the racemate of Rasagiline. (Rac)-Rasagiline is a selective type B MAO (MAO-B) inhibitor. (Rac)-Rasagiline can be used for Parkinson's disease research. (Rac)-Rasagiline protects against MPTP (HY-15608)-induced toxicity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(Rac)-Rasagiline | 97.0% | (Rac)-Rasagiline (AGN1135) is the racemate of Rasagiline. (Rac)-Rasagiline is a selective type B MAO (MAO-B) inhibitor. (Rac)-Rasagiline can be used for Parkinson's disease research. (Rac)-Rasagiline protects against MPTP (HY-15608)-induced toxicity. | ||||||||||||||||||||
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Indantadol | Indantadol (the free base of CHF-3381) is an orally active, non-selective NMDA antagonist and MAO inhibitor. Indantadol blocks the binding of [³H]-MK-801 to NMDA receptors in a non-competitive manner, with an IC50 of 8.1 μM. Indantadol completely inhibits dopamine release caused by NMDA. Indantadol protects neurons, with an ED₅₀ of 35 μM. Indantadol has anticonvulsant and anti-high pain hypersensitivity activities. | |||||||||||||||||||||
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Indantadol hydrochloride | Indantadol hydrochloride (CHF-3381) is an orally active, non-selective NMDA antagonist and MAO inhibitor. Indantadol hydrochloride blocks the binding of [³H]-MK-801 to NMDA receptors in a non-competitive manner, with an IC50 of 8.1 μM. Indantadol hydrochloride completely inhibits dopamine release caused by NMDA. Indantadol hydrochloride protects neurons, with an ED₅₀ of 35 μM. Indantadol hydrochloride has anticonvulsant and anti-high pain hypersensitivity activities. | |||||||||||||||||||||
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N-Methylindan-2-amine hydrochloride | 98.0% | N-Methylindan-2-amine hydrochloride (compound 3b) is an N-alkylated congener of phenylethylamine that increases hot plate reaction time in mice without inducing dopaminergic effects. N-Methylindan-2-amine hydrochloride can be used to study central noradrenergic mechanisms. | ||||||||||||||||||||
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Nordeprenyl | 95.13% | Nordeprenyl is the metabolite of Deprenyl. Deprenyl is a potent, selective and irreversible inhibitor of MAO-B. Nordeprenyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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(S)-Rasagiline | 99.80% | (S)-Rasagiline (TVP1022) is the relatively inactive S-enantiomer form of Rasagiline. Rasagiline is a highly potent selective irreversible MAO inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively. (S)-Rasagiline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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2-PAT | 2-PAT, an analogue of Rasagiline and Selegiline, a reversible MAO-A inhibitor with an IC50 of 0.721 µM. 2-PAT is an inactivator of MAO-B with an IC50 of 14.6 µM. 2-PAT has the potential for Parkinson’s disease and depression research. | |||||||||||||||||||||
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Rasagiline | 99.97% | Rasagiline (R-AGN1135) is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively. Rasagiline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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1-Aminoindan | 99.29% | 1-Aminoindan (1-Indanamine; 2,3-Dihydro-1H-inden-1-amine) is an α-synuclein (α-synuclein) binder. By binding to α-synuclein, 1-Aminoindan promotes the formation of its neuroprotective "cyclic" conformation, thereby reducing the misfolding and aggregation of α-synuclein. 1-Aminoindan is a metabolite of Rasagiline (HY-14605A). 1-Aminoindan can be used in research related to Parkinson's disease. | ||||||||||||||||||||
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(S)-2-Benzylpyrrolidine | (S)-2-Benzylpyrrolidine (Compound s1) serves as a METH hapten scaffold. (S)-2-Benzylpyrrolidine attenuates Methamphetamine-induced hyperlocomotion, hyperthermia and respiratory depression. (S)-2-Benzylpyrrolidine alleviates sedative agent-induced respiratory depression. | |||||||||||||||||||||
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Ranolazine impurity 5 | Ranolazine impurity 5 is an impurity of Ranolazine. | |||||||||||||||||||||
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