1886973-05-2
Chemical Structure
Elabela(19-32)
- CAS No.: 1886973-05-2
- Formula:C75H119N25O17S2
- Molecular Weight:1707.03
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: O=C([C@@H]1CCC(N1)=O)N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CS)C(N[C@@H](CCSC)C(N2[C@@H](CCC2)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(N5[C@@H](CCC5)C(O)=O)=O)=O)=O)=O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)=O
Biological Activity: Elabela(19-32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Elabela(19-32) | 98.18% | Elabela(19-32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
