21392-57-4
21392-57-4
Chemical Structure
5,7-Dimethoxyflavone
- CAS No.: 21392-57-4
- Formula:C17H14O4
- Molecular Weight:282.29
IUPAC Name: 5,7-dimethoxy-2-phenyl-4H-chromen-4-one
InChIKey: JRFZSUMZAUHNSL-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=CC=C2)OC3=CC(OC)=CC(OC)=C13
Biological Activity: 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2].
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5,7-Dimethoxyflavone | 99.52% | 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor. | ||||||||||||||||||||
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5,7-Dimethoxyflavone (Standard) | 99.55% | 5,7-Dimethoxyflavone (Standard) is the analytical standard of 5,7-Dimethoxyflavone. This product is intended for research and analytical applications. 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor. | ||||||||||||||||||||
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References
- [1]. Ochiai W, et al. Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam. J Nat Med. 2018 Jun;72(3):607-614. [Content Brief]
- [2]. Bae S, et al. Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice. Eur J Pharm Sci. 2018 May 30;117:27-34. [Content Brief]
