21392-57-4
21392-57-4
Chemical Structure
5,7-Dimethoxyflavone
- CAS No.: 21392-57-4
- Formula:C17H14O4
- Molecular Weight:282.29
IUPAC Name: 5,7-dimethoxy-2-phenyl-4H-chromen-4-one
InChIKey: JRFZSUMZAUHNSL-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=CC=C2)OC3=CC(OC)=CC(OC)=C13
Biological Activity: 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
5,7-Dimethoxyflavone | 99.52% | 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
5,7-Dimethoxyflavone (Standard) | 99.55% | 5,7-Dimethoxyflavone (Standard) is the analytical standard of 5,7-Dimethoxyflavone. This product is intended for research and analytical applications. 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.88
HY-14592Tectochrysin -
Similarity Score 0.84
HY-N68185,7,4'-Trimethoxyflavone -
Similarity Score 0.83
HY-N2036Mosloflavone -
Similarity Score 0.83
HY-107790R5-Methoxyflavone (Standard) -
Similarity Score 0.82
HY-1103985,6,7-Trimethoxyflavone -
Similarity Score 0.82
HY-N178505-Hydroxy-6,7-dimethoxyflavone -
Similarity Score 0.82
HY-1119285,7-Dimethoxyluteolin -
Similarity Score 0.81
HY-N4285Negletein -
Similarity Score 0.80
HY-N21447,4'-Di-O-methylapigenin -
Explore the MedChemAI to find more analogs
References
- [1]. Ochiai W, et al. Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam. J Nat Med. 2018 Jun;72(3):607-614. [Content Brief]
- [2]. Bae S, et al. Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice. Eur J Pharm Sci. 2018 May 30;117:27-34. [Content Brief]
