5,7-Dimethoxyflavone (Standard)
Based on 1 Customer Validation
5,7-Dimethoxyflavone (Standard) is the analytical standard of 5,7-Dimethoxyflavone. This product is intended for research and analytical applications. 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.55%
- No. CAS: 21392-57-4
- Fòrmula: C17H14O4
- Peso molecular:282.29
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Pureza y Documentación
-
Help & FAQs
-
HY-N5011
5,7-DimethoxyflavoneBCRP Inhibitor -
HY-N0155
NobiletinROR Agonist -
HY-N0382
GalanginCytochrome P450 Inhibitor -
HY-N0014
IcariinPPAR Activator -
HY-N0168
HesperetinUGT Inhibitor -
HY-N0451
AcacetinAutophagy Inducer -
HY-N1201
ApigeninCytochrome P450 Inhibitor -
HY-N0133
TangeretinApoptosis Inducer -
HY-N2229
RhapontigeninCytochrome P450 1A1 Inactivator -
HY-N0101
NeohesperidinWnt/β-Catenin Activator -
HY-N0014R
Icariin (Standard) -
HY-103389
1-AminobenzotriazoleCytochrome P450 Inhibitor
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
No. CAS 21392-57-4
-
Appearance Solid
-
Peso molecular 282.29
-
Fòrmula C17H14O4
-
Color White to off-white
-
SMILES
O=C1C=C(C2=CC=CC=C2)OC3=CC(OC)=CC(OC)=C13
-
Structure Classification
-
Initial Source
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
[1]. Ochiai W, et al. Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam. J Nat Med. 2018 Jun;72(3):607-614. [Content Brief]
[2]. Bae S, et al. Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice. Eur J Pharm Sci. 2018 May 30;117:27-34. [Content Brief]
[3]. Kim C, Hwang JK. The 5,7-Dimethoxyflavone Suppresses Sarcopenia by Regulating Protein Turnover and Mitochondria Biogenesis-Related Pathways. Nutrients. 2020 Apr 13;12(4):1079. [Content Brief]
[4]. Kang YG, et al. 5,7-dimethoxyflavone induces melanogenesis in B16F10 melanoma cells through cAMP-dependent signalling. Exp Dermatol. 2011 May;20(5):445-7. [Content Brief]
[5]. Song Y, et al. 5,7-Dimethoxyflavone Attenuates Obesity by Inhibiting Adipogenesis in 3T3-L1 Adipocytes and High-Fat Diet-Induced Obese C57BL/6J Mice. J Med Food. 2016 Dec;19(12):1111-1119. [Content Brief]
[6]. Park W, et al. 5,7-Dimethoxyflavone induces apoptotic cell death in human endometriosis cell lines by activating the endoplasmic reticulum stress pathway. Phytother Res. 2020 Sep;34(9):2275-2286. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5,7-Dimethoxyflavone (Standard) Related Classifications
HY-N5011R Related Classifications
Powered by Bioz