21888-98-2
21888-98-2
Chemical Structure
Dexetimide
Synonym(s): (+)-Benzetimide; (S)-(+)-Dexetimide; Dexbenzetimide
- CAS. Nr.: 21888-98-2
- Formula:C23H26N2O2
- Molecular Weight:362.46
IUPAC Name: (S)-1'-benzyl-3-phenyl-[3,4'-bipiperidine]-2,6-dione
InChIKey: LQQIVYSCPWCSSD-HSZRJFAPSA-N
SMILES: O=C(N1)[C@@](C2CCN(CC3=CC=CC=C3)CC2)(C4=CC=CC=C4)CCC1=O
Biological Activity: Dexetimide ((+)-Benzetimide; (S)-(+)-Dexetimide; Dexbenzetimide) is a piperidine anticholinergic and a high-affinity muscarinic receptor antagonist. Dexetimide can be used in studies of parkinson's disease[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Dexetimide | 99.94% | Dexetimide ((+)-Benzetimide; (S)-(+)-Dexetimide; Dexbenzetimide) is a piperidine anticholinergic and a high-affinity muscarinic receptor antagonist. Dexetimide can be used in studies of parkinson's disease. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-105545ALevetimide -
Similarity Score 0.98
HY-105545CDexetimide hydrochloride -
Similarity Score 0.98
HY-B1547ABenzetimide hydrochloride -
Similarity Score 0.86
HY-12426mAChR-IN-1 -
Similarity Score 0.85
HY-12426AmAChR-IN-1 hydrochloride -
Similarity Score 0.83
HY-100265Cinperene -
Similarity Score 0.70
HY-43711Nor-benzetimide -
Similarity Score 0.58
HY-180296AChE-IN-103 -
Similarity Score 0.58
HY-139223pEBOV-IN-1 -
Explore the MedChemAI to find more analogs
References
- [1]. Speck AL, et al. The absolute configuration and crystal structure of the anticholinergic drug dexbenzetimide. Nature. 1971 Aug 20;232(5312):575-6. [Content Brief]
- [2]. Müller-Gärtner HW, et al. Imaging muscarinic cholinergic receptors in human brain in vivo with Spect, [123I]4-iododexetimide, and [123I]4-iodolevetimide. J Cereb Blood Flow Metab. 1992 Jul;12(4):562-70. [Content Brief]
