2201056-66-6
2201056-66-6
Chemical Structure
AG-270
- CAS No.: 2201056-66-6
- Formula:C30H27N5O2
- Molecular Weight:489.57
IUPAC Name: 3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
InChIKey: HSVRUECLQUGTDS-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC=C(OC)C=C2)=C(NC3=NC=CC=C3)NC4=C(C5=CCCCC5)C(C6=CC=CC=C6)=NN14
Biological Activity:
AG-270 is an allosteric, noncompetitive, first-in-class, reversible and orally active MAT2A inhibitor, with an IC50 of 14 nM[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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AG-270 | 99.97% | AG-270 is an allosteric, noncompetitive, first-in-class, reversible and orally active MAT2A inhibitor, with an IC50 of 14 nM. |
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Structural Analogs
-
Similarity Score 0.65
HY-112131MAT2A inhibitor 1 -
Similarity Score 0.58
HY-182400AGI-25696 -
Similarity Score 0.54
HY-112129AGI25696-analog -
Similarity Score 0.53
HY-112130AGI-24512 -
Similarity Score 0.51
HY-115924CDK1-IN-1 -
Similarity Score 0.48
HY-112473Grassofermata -
Similarity Score 0.48
HY-116696GSK3-IN-11 -
Similarity Score 0.46
HY-108232RMK-2206 (Standard) -
Similarity Score 0.46
HY-147214GNE-7883 -
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