2226227-75-2
2226227-75-2
Chemical Structure
ATG7-IN-2
- CAS No.: 2226227-75-2
- Formula:C11H16N6O7S
- Molecular Weight:376.35
IUPAC Name: ((2R,3S,4R,5R)-5-(4-amino-3-methoxy-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl sulfamate
InChIKey: SVHOPJCSYNTLAH-RPKMEZRRSA-N
SMILES: O[C@H]1[C@](O[C@@H]([C@H]1O)COS(N)(=O)=O)([H])N2C3=NC=NC(N)=C3C(OC)=N2
Biological Activity: ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ATG7-IN-2 | 99.32% | ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.87
HY-171215ML901 -
Similarity Score 0.78
HY-161905ML471 -
Similarity Score 0.65
HY-146131ATG7-IN-3 -
Similarity Score 0.65
HY-182503GP515 -
Similarity Score 0.60
HY-101136Dealanylascamycin -
Similarity Score 0.58
![4-Methoxy-1-β-D-ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine Chemical Structure](//file.medchemexpress.com/product_pic/hy-152827.gif)
HY-1528274-Methoxy-1-β-D-ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine -
Similarity Score 0.58
HY-108940GlyRS-IN-1 -
Similarity Score 0.57
![6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine Chemical Structure](//file.medchemexpress.com/product_pic/hy-152438.gif)
HY-1524386-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine -
Similarity Score 0.57
![2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine Chemical Structure](//file.medchemexpress.com/product_pic/hy-152408.gif)
HY-1524082-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine -
Explore the MedChemAI to find more analogs
![4-Methoxy-1-β-D-ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-152827.gif)
![6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-152438.gif)
![2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-152408.gif)
