2375846-41-4
Chemical Structure
DVD-445
- No. CAS: 2375846-41-4
- Formula:C25H28F2N2O4
- Molecular Weight:458.50
IUPAC Name: 2-((2-(tert-butylamino)-1-(4-fluorophenyl)-2-oxoethyl)(methyl)amino)ethyl (E)-4-(4-fluorophenyl)-4-oxobut-2-enoate
InChIKey: RJGWWNVHLMPYEN-BUHFOSPRSA-N
SMILES: O=C(OCCN(C(C1=CC=C(F)C=C1)C(NC(C)(C)C)=O)C)/C=C/C(C2=CC=C(F)C=C2)=O
Biological Activity: DVD-445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC50 of 0.60 μM for rat TrxR1. DVD-445 has good anticancer application[1].
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DVD-445 | 98.36% | DVD-445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC50 of 0.60 μM for rat TrxR1. DVD-445 has good anticancer application. | ||||||||||||||||||||
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Keywords