2465-27-2
2465-27-2
Chemical Structure
Auramine O
- CAS No.: 2465-27-2
- Formula:C17H22ClN3
- Molecular Weight:303.84
IUPAC Name: 4,4'-(iminomethylene)bis(N,N-dimethylaniline) hydrochloride
InChIKey: KSCQDDRPFHTIRL-UHFFFAOYSA-N
SMILES: N=C(C1=CC=C(N(C)C)C=C1)C2=CC=C(N(C)C)C=C2.[H]Cl
Biological Activity: Auramine O is a yellow fluorescent dye. Auramine O is used to detect amyloid fibrils. Auramine O promotes lung malignancy. Auramine O is also used to determine algal cell viability and stain acid-fast bacteria[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Auramine O | 83.12% | Auramine O is a yellow fluorescent dye. Auramine O is used to detect amyloid fibrils. Auramine O promotes lung malignancy. Auramine O is also used to determine algal cell viability and stain acid-fast bacteria. | ||||||||||||||||||||
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tau-0N4R-IN-1 | tau-0N4R-IN-1 (Compound 6T) is an BBB-penetrable inhibitor of tau 0N4R oligomerization. tau-0N4R-IN-1 effectively inhibits the fibrosis of tau 0N4R, 2N3R, and 2N4R, exhibits an anti-seeding effect on tau in vitro, reduces the oligomerization of α-syn dose-dependently, and prevents formation of α-syn inclusions. tau-0N4R-IN-1 is stable in mouse microsomes and reduces Aβ plaques in brain tissues from AD patients. tau-0N4R-IN-1 has good pharmacokinetic properties in mice. | |||||||||||||||||||||
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C.I. Basic yellow 37 | C.I. Basic yellow 37 is an alkaline dye that can be removed from aqueous solutions in intermittent adsorption systems using tree ferns as biosorbents. | |||||||||||||||||||||
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Dabcyl acid | 99.49% | Dabcyl acid (Dabcyl) is a nonfluorescent chromophore and a quencher. Dabcyl acid can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions. | ||||||||||||||||||||
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Dabcyl acid sodium | Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions. | |||||||||||||||||||||
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4-(N,N-Dimethylamino)azobenzene-4'-isothiocyanate | 4-(N,N-Dimethylamino)azobenzene-4'-isothiocyanate is a chromophoric, hydrophobic reagent for probing membrane-buried segments of intrinsic proteins. | |||||||||||||||||||||
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Stilbamidine | Stilbamidine is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections. | |||||||||||||||||||||
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Thiomichler's ketone | 81.08% | Thiomichler's ketone (4,4'-Bis (dimethylamino) thiobenzophenone) is a heavy metal complexing agent and a colorimetric/spectrophotometric reagent. Thiomichler's ketone shows selectivity for Hg2+ at pH 3, and exhibits activity towards Pd2+ and Ag+ at pH 3.5. Thiomichler's ketone enables accurate detection of trace Pd2+ by forming an extractable Hg2+ complex via micelle-mediated cloud point extraction, or generating a red coordination complex including Pd (TMK)4. Thiomichler's ketone is applicable for the determination of trace Pd2+ in antibiotics and catalysts of automobile exhaust purifiers. | ||||||||||||||||||||
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4,4′-Diaminobenzophenone | 4,4′-Diaminobenzophenone (Compound 8h) is a building block. 4,4′-Diaminobenzophenone is widely used in the dye industry as an intermediate in dyes, pigments and photosensitive materials. | |||||||||||||||||||||
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Methyl yellow | Methyl yellow (Solvent Yellow 2) is a pH indicator. Methyl yellow appears red at low pH, and becomes yellow above pH 4.0. | |||||||||||||||||||||
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m-Methyl red | m-Methyl red is a biological material or organic compound that can be used in life science research. | |||||||||||||||||||||
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References
- [1]. Kommareddi S, et al. Nontuberculous mycobacterial infections: comparison of the fluorescent auramine-O and Ziehl-Neelsen techniques in tissue diagnosis. Hum Pathol. 1984 Nov;15(11):1085-9. [Content Brief]
- [2]. Hosseinpour S A, et al. Use of metal composite MOF‐5‐Ag2O‐NPs as an adsorbent for the removal of Auramine O dye under ultrasound energy conditions. Applied Organometallic Chemistry, 2018, 32(2): e4007.
- [3]. Gizaw N, et al. The yield of Auramine O staining using led microscopy with bleach treated sputum samples for detection of pulmonary tuberculosis at St. Peter tuberculosis specialized hospital, Addis Ababa, Ethiopia. J Clin Tuberc Other Mycobact Dis. 2019 Dec 12;18:100140. [Content Brief]
- [4]. Amdursky N, et al. Auramine-O as a fluorescence marker for the detection of amyloid fibrils. J Phys Chem B. 2012 Nov 15;116(45):13389-95. [Content Brief]
- [5]. Tung JC, et al. Auramine O, an incense smoke ingredient, promotes lung cancer malignancy. Environ Toxicol. 2017 Nov;32(11):2379-2391. [Content Brief]
- [6]. Hawes I, et al. Use of the fluorochrome Auramine O for determination of cell viability in filamentous and thalloid algae. Phycologia, 1989, 28(4): 518-520.
