2465-27-2
Chemical Structure
Auramine O
- CAS. Nr.: 2465-27-2
- Formula:C17H22ClN3
- Molecular Weight:303.84
IUPAC Name: 4,4'-(iminomethylene)bis(N,N-dimethylaniline) hydrochloride
InChIKey: KSCQDDRPFHTIRL-UHFFFAOYSA-N
SMILES: N=C(C1=CC=C(N(C)C)C=C1)C2=CC=C(N(C)C)C=C2.[H]Cl
Biological Activity: Auramine O is a yellow fluorescent dye. Auramine O is used to detect amyloid fibrils. Auramine O promotes lung malignancy. Auramine O is also used to determine algal cell viability and stain acid-fast bacteria[1][2][3][4][5][6].
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Auramine O | 83.12% | Auramine O is a yellow fluorescent dye. Auramine O is used to detect amyloid fibrils. Auramine O promotes lung malignancy. Auramine O is also used to determine algal cell viability and stain acid-fast bacteria. | ||||||||||||||||||||
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Similarity Score 0.87
HY-W009311Thiomichler's ketone -
Similarity Score 0.75
HY-D0406C.I. Basic yellow 37 -
Similarity Score 0.69
HY-D1045Dabcyl acid -
Similarity Score 0.68
HY-D1045ADabcyl acid sodium -
Similarity Score 0.67
HY-159941tau-0N4R-IN-1 -
Similarity Score 0.66
HY-D15054-(N,N-Dimethylamino)azobenzene-4'-isothiocyanate -
Similarity Score 0.66
HY-W0142904,4′-Diaminobenzophenone -
Similarity Score 0.66
HY-U00007Stilbamidine -
Similarity Score 0.65
HY-W025785Methyl yellow -
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References
- [1]. Kommareddi S, et al. Nontuberculous mycobacterial infections: comparison of the fluorescent auramine-O and Ziehl-Neelsen techniques in tissue diagnosis. Hum Pathol. 1984 Nov;15(11):1085-9. [Content Brief]
- [2]. Hosseinpour S A, et al. Use of metal composite MOF‐5‐Ag2O‐NPs as an adsorbent for the removal of Auramine O dye under ultrasound energy conditions. Applied Organometallic Chemistry, 2018, 32(2): e4007.
- [3]. Gizaw N, et al. The yield of Auramine O staining using led microscopy with bleach treated sputum samples for detection of pulmonary tuberculosis at St. Peter tuberculosis specialized hospital, Addis Ababa, Ethiopia. J Clin Tuberc Other Mycobact Dis. 2019 Dec 12;18:100140. [Content Brief]
- [4]. Amdursky N, et al. Auramine-O as a fluorescence marker for the detection of amyloid fibrils. J Phys Chem B. 2012 Nov 15;116(45):13389-95. [Content Brief]
- [5]. Tung JC, et al. Auramine O, an incense smoke ingredient, promotes lung cancer malignancy. Environ Toxicol. 2017 Nov;32(11):2379-2391. [Content Brief]
- [6]. Hawes I, et al. Use of the fluorochrome Auramine O for determination of cell viability in filamentous and thalloid algae. Phycologia, 1989, 28(4): 518-520.