302941-52-2
302941-52-2
Chemical Structure
DUPA
- CAS No.: 302941-52-2
- Formula:C11H16N2O9
- Molecular Weight:320.25
IUPAC Name: (2S,2'S)-2,2'-(carbonylbis(azanediyl))diglutaric acid
InChIKey: SOAPXKSPJAZNGO-WDSKDSINSA-N
SMILES: O=C(N[C@](CCC(O)=O)([H])C(O)=O)N[C@](CCC(O)=O)([H])C(O)=O
Biological Activity: DUPA, belongs to a class of glutamate ureas, is used as the targeting moiety in agent conjugate to selectively deliver cytotoxic agents to prostate cancer cells[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DUPA | 98.0% | DUPA, belongs to a class of glutamate ureas, is used as the targeting moiety in agent conjugate to selectively deliver cytotoxic agents to prostate cancer cells. | ||||||||||||||||||||
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DUPA (Standard) | ≥98% | DUPA (Standard) is the analytical standard of DUPA (HY-111606). This product is intended for research and analytical applications. DUPA, belongs to a class of glutamate ureas, is used as the targeting moiety in agent conjugate to selectively deliver cytotoxic agents to prostate cancer cells. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.85
HY-139840GCPII-IN-1 -
Similarity Score 0.83
HY-103344ZJ43 -
Similarity Score 0.81
HY-W127814Ethylenediamine-N,N′-diglutaric acid -
Similarity Score 0.78
HY-130553β-Spaglumic acid -
Similarity Score 0.78
HY-139840AGCPII-IN-1 TFA -
Similarity Score 0.78
HY-W016012Glu-Glu -
Similarity Score 0.77
HY-100921Spaglumic acid -
Similarity Score 0.76
HY-118090L-γ-Glutamyl-L-glutamic acid -
Similarity Score 0.76
HY-118090AD-γ-Glutamyl-D-glutamic acid -
Explore the MedChemAI to find more analogs
References
- [1]. Peng ZH, et al. Spacer length impacts the efficacy of targeted docetaxel conjugates in prostate-specific membrane antigen expressing prostate cancer. J Drug Target. 2013 Dec;21(10):968-80. [Content Brief]
- [2]. Roy J, et al. DUPA conjugation of a cytotoxic indenoisoquinoline topoisomerase I inhibitor for selective prostate cancer cell targeting. J Med Chem. 2015 Apr 9;58(7):3094-103. [Content Brief]
