32747-08-3
Chemical Structure
Glycohyocholic acid
Synonym(s): GHCA
- CAS No.: 32747-08-3
- Formula:C26H43NO6
- Molecular Weight:465.62
IUPAC Name: ((R)-4-((3R,5R,6R,7S,8S,9S,10R,13R,14S,17R)-3,6,7-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoyl)glycine
InChIKey: ZQYUKJFJPJDMMR-ZDWCHQGWSA-N
SMILES: O[C@@H]1CC[C@]2([C@@]([H])(C1)[C@H]([C@H]([C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@@]4([C@@H](CCC(NCC(O)=O)=O)C)[H])[H])C)[H])[H])O)O)C
Biological Activity: Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Hyocholic acid (HY-121238) and Glycine (HY-Y0966). Glycohyocholic acid can be used as a biomarker in the study of hepatitis C-related cirrhosis and diabetes[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Glycohyocholic acid | 99.93% | Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Hyocholic acid (HY-121238) and Glycine (HY-Y0966). Glycohyocholic acid can be used as a biomarker in the study of hepatitis C-related cirrhosis and diabetes. | ||||||||||||||||||||
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Glycohyocholic acid (Standard) | 99.92% | Glycohyocholic acid (Standard) is the analytical standard of Glycohyocholic acid (HY-122141). This product is intended for use in research and analytical applications. Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Cholic acid (HY-N0324) and Glycine (HY-Y0966). Glycohyocholic acid can be used in the study of hepatitis C-related cirrhosis and diabetes mellitus. | ||||||||||||||||||||
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Glycohyocholic acid-d4 | Glycohyocholic acid-d4 is the deuterium labeled Glycohyocholic acid (HY-122141). Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Cholic acid (HY-N0324) and Glycine (HY-Y0966). Glycohyocholic acid can be used in the study of hepatitis C-related cirrhosis and diabetes mellitus. | |||||||||||||||||||||
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References
- [1]. Fitian AI, et al. Integrated metabolomic profiling of hepatocellular carcinoma in hepatitis C cirrhosis through GC/MS and UPLC/MS-MS. Liver Int. 2014 Oct;34(9):1428-44. [Content Brief]
- [2]. Xiaojiao Zheng, et al. Hyocholic acid species and the risk of type 2 diabetes. bioRxiv. December 21, 2018.
